Compile Data Set for Download or QSAR
maximum 50k data
Found 5 Enz. Inhib. hit(s) with all data for entry = 8629
TargetTransthyretin(Homo sapiens (Human))
Bsim Therapeutics

US Patent
LigandPNGBDBM408979(US10377729, Compound 2OH-PCB80)
Affinity DataIC50:  1.59E+3nMAssay Description:In vitro evaluation of inhibitory activity against WT-TTR amyloid fibril formation of AT09 and reference compounds. Reference compounds (thyroxine, t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransthyretin(Homo sapiens (Human))
Bsim Therapeutics

US Patent
LigandPNGBDBM408976(US10377729, Compound AT09-B00)
Affinity DataIC50:  2.02E+3nMAssay Description:In vitro evaluation of inhibitory activity against WT-TTR amyloid fibril formation of AT09 and reference compounds. Reference compounds (thyroxine, t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransthyretin(Homo sapiens (Human))
Bsim Therapeutics

US Patent
LigandPNGBDBM408980(Thyroxine | US10377729, T4)
Affinity DataIC50:  2.20E+3nMAssay Description:In vitro evaluation of inhibitory activity against WT-TTR amyloid fibril formation of AT09 and reference compounds. Reference compounds (thyroxine, t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransthyretin(Homo sapiens (Human))
Bsim Therapeutics

US Patent
LigandPNGBDBM408977(US10377729, Compound AT09-B06)
Affinity DataIC50:  2.49E+3nMAssay Description:In vitro evaluation of inhibitory activity against WT-TTR amyloid fibril formation of AT09 and reference compounds. Reference compounds (thyroxine, t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransthyretin(Homo sapiens (Human))
Bsim Therapeutics

US Patent
LigandPNGBDBM50197883(CHEBI:78538 | FX-1006 | Tafamidis | US10377729, Co...)
Affinity DataIC50:  3.10E+3nMAssay Description:In vitro evaluation of inhibitory activity against WT-TTR amyloid fibril formation of AT09 and reference compounds. Reference compounds (thyroxine, t...More data for this Ligand-Target Pair