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Found 27 Enz. Inhib. hit(s) with all data for entry = 9771
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM487146(US10952995, Compound 1-3)
Affinity DataKi:  0.900nMAssay Description:The presently disclosed compounds find use in inhibiting the activity of the enzyme HPK1. HPK1, also referred to as mitogen activated protein kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM487163(US10952995, Compound 1-19)
Affinity DataKi:  1nMAssay Description:The presently disclosed compounds find use in inhibiting the activity of the enzyme HPK1. HPK1, also referred to as mitogen activated protein kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM487144(US10952995, Compound 1-1)
Affinity DataKi:  2nMAssay Description:The presently disclosed compounds find use in inhibiting the activity of the enzyme HPK1. HPK1, also referred to as mitogen activated protein kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM487148(US10952995, Compound 1-5)
Affinity DataKi:  2nMAssay Description:The presently disclosed compounds find use in inhibiting the activity of the enzyme HPK1. HPK1, also referred to as mitogen activated protein kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM487171(6-amino-3-(2-chloro-3-ethyl- 1H-pyrrolo[2,3-b]pyri...)
Affinity DataKi:  2.70nMAssay Description:The presently disclosed compounds find use in inhibiting the activity of the enzyme HPK1. HPK1, also referred to as mitogen activated protein kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM487145(US10952995, Compound 1-2)
Affinity DataKi:  3nMAssay Description:The presently disclosed compounds find use in inhibiting the activity of the enzyme HPK1. HPK1, also referred to as mitogen activated protein kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM487161(US10952995, Compound 1-18)
Affinity DataKi:  4nMAssay Description:The presently disclosed compounds find use in inhibiting the activity of the enzyme HPK1. HPK1, also referred to as mitogen activated protein kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM487166(2-amino-5-(2,4-dichloro-3-(2- hydroxyethyl)-1H-pyr...)
Affinity DataKi:  9.40nMAssay Description:The presently disclosed compounds find use in inhibiting the activity of the enzyme HPK1. HPK1, also referred to as mitogen activated protein kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM487170(6-amino-3-(2,4-dichloro-3-(2- hydroxyethyl)-1H-pyr...)
Affinity DataKi:  12nMAssay Description:The presently disclosed compounds find use in inhibiting the activity of the enzyme HPK1. HPK1, also referred to as mitogen activated protein kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM487154(US10952995, Compound 1-11)
Affinity DataKi:  13nMAssay Description:The presently disclosed compounds find use in inhibiting the activity of the enzyme HPK1. HPK1, also referred to as mitogen activated protein kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM487147(US10952995, Compound 1-4)
Affinity DataKi:  15nMAssay Description:The presently disclosed compounds find use in inhibiting the activity of the enzyme HPK1. HPK1, also referred to as mitogen activated protein kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM487149(US10952995, Compound 1-6)
Affinity DataKi:  15nMAssay Description:The presently disclosed compounds find use in inhibiting the activity of the enzyme HPK1. HPK1, also referred to as mitogen activated protein kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM487157(US10952995, Compound 1-14)
Affinity DataKi:  17nMAssay Description:The presently disclosed compounds find use in inhibiting the activity of the enzyme HPK1. HPK1, also referred to as mitogen activated protein kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM487164(US10952995, Compound 1-20)
Affinity DataKi:  17nMAssay Description:The presently disclosed compounds find use in inhibiting the activity of the enzyme HPK1. HPK1, also referred to as mitogen activated protein kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM487155(US10952995, Compound 1-12)
Affinity DataKi:  24nMAssay Description:The presently disclosed compounds find use in inhibiting the activity of the enzyme HPK1. HPK1, also referred to as mitogen activated protein kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM487169(3-(3-(2-chloro-3-ethyl-1H- pyrrolo[2,3-b]pyridin-5...)
Affinity DataKi:  31nMAssay Description:The presently disclosed compounds find use in inhibiting the activity of the enzyme HPK1. HPK1, also referred to as mitogen activated protein kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM487153(US10952995, Compound 1-10)
Affinity DataKi:  32nMAssay Description:The presently disclosed compounds find use in inhibiting the activity of the enzyme HPK1. HPK1, also referred to as mitogen activated protein kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM487168(3-(4-(2-chloro-3-ethyl-1H- pyrrolo[2,3-b]pyridin-5...)
Affinity DataKi:  32nMAssay Description:The presently disclosed compounds find use in inhibiting the activity of the enzyme HPK1. HPK1, also referred to as mitogen activated protein kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM487150(US10952995, Compound 1-7)
Affinity DataKi:  33nMAssay Description:The presently disclosed compounds find use in inhibiting the activity of the enzyme HPK1. HPK1, also referred to as mitogen activated protein kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM487151(US10952995, Compound 1-8)
Affinity DataKi:  68nMAssay Description:The presently disclosed compounds find use in inhibiting the activity of the enzyme HPK1. HPK1, also referred to as mitogen activated protein kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM487158(US10952995, Compound 1-15)
Affinity DataKi:  75nMAssay Description:The presently disclosed compounds find use in inhibiting the activity of the enzyme HPK1. HPK1, also referred to as mitogen activated protein kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM487152(US10952995, Compound 1-9)
Affinity DataKi:  76nMAssay Description:The presently disclosed compounds find use in inhibiting the activity of the enzyme HPK1. HPK1, also referred to as mitogen activated protein kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM487159(US10952995, Compound 1-16)
Affinity DataKi:  82nMAssay Description:The presently disclosed compounds find use in inhibiting the activity of the enzyme HPK1. HPK1, also referred to as mitogen activated protein kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM487165(US10952995, Compound 1-21)
Affinity DataKi:  89nMAssay Description:The presently disclosed compounds find use in inhibiting the activity of the enzyme HPK1. HPK1, also referred to as mitogen activated protein kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM487167(6-amino-3-(2-chloro-3- (methoxymethyl)-1H- pyrrolo...)
Affinity DataKi:  160nMAssay Description:The presently disclosed compounds find use in inhibiting the activity of the enzyme HPK1. HPK1, also referred to as mitogen activated protein kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM487160(US10952995, Compound 1-17)
Affinity DataKi:  1.30E+3nMAssay Description:The presently disclosed compounds find use in inhibiting the activity of the enzyme HPK1. HPK1, also referred to as mitogen activated protein kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM487156(US10952995, Compound 1-13)
Affinity DataKi:  1.70E+3nMAssay Description:The presently disclosed compounds find use in inhibiting the activity of the enzyme HPK1. HPK1, also referred to as mitogen activated protein kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent