Compile Data Set for Download or QSAR
maximum 50k data
Found 16 Enz. Inhib. hit(s) with all data for entry = 9838
TargetBile acid receptor(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM461247(2-(3-(2-chloro-4-((5- cyclopropyl-3-(2,4- difluoro...)
Affinity DataEC50:  263nMAssay Description:Determination of a ligand mediated cofactor peptide interaction to quantify ligand binding to the nuclear receptor FXR was performed as follows.Prepa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM461254((6-(3-(2-chloro-4-((5- cyclopropyl-3-(2,6-dichloro...)
Affinity DataEC50:  1.26E+3nMAssay Description:Determination of a ligand mediated Gal4 promoter driven transactivation to quantify ligand binding mediated activation of FXR was performed as follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM461248(2-(3-(2-chloro-4-((5- cyclopropyl-3-(2,6-dichloro-...)
Affinity DataEC50:  25nMAssay Description:Determination of a ligand mediated cofactor peptide interaction to quantify ligand binding to the nuclear receptor FXR was performed as follows.Prepa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM461248(2-(3-(2-chloro-4-((5- cyclopropyl-3-(2,6-dichloro-...)
Affinity DataEC50:  831nMAssay Description:Determination of a ligand mediated Gal4 promoter driven transactivation to quantify ligand binding mediated activation of FXR was performed as follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM461249(6-(3-(2-chloro-4-((5- cyclopropyl-3-(2,6-dichloro-...)
Affinity DataEC50:  7.40nMAssay Description:Determination of a ligand mediated cofactor peptide interaction to quantify ligand binding to the nuclear receptor FXR was performed as follows.Prepa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM461249(6-(3-(2-chloro-4-((5- cyclopropyl-3-(2,6-dichloro-...)
Affinity DataEC50:  3.80nMAssay Description:Determination of a ligand mediated Gal4 promoter driven transactivation to quantify ligand binding mediated activation of FXR was performed as follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM461250(6-(3-(2-chloro-4-((3-(2,6- dichloro-4-fluorophenyl...)
Affinity DataEC50:  35nMAssay Description:Determination of a ligand mediated cofactor peptide interaction to quantify ligand binding to the nuclear receptor FXR was performed as follows.Prepa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM461250(6-(3-(2-chloro-4-((3-(2,6- dichloro-4-fluorophenyl...)
Affinity DataEC50:  176nMAssay Description:Determination of a ligand mediated Gal4 promoter driven transactivation to quantify ligand binding mediated activation of FXR was performed as follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM461251(6-(3-(2-chloro-4-((4- cyclopropyl-1-(2,6-dichloro-...)
Affinity DataEC50:  18nMAssay Description:Determination of a ligand mediated cofactor peptide interaction to quantify ligand binding to the nuclear receptor FXR was performed as follows.Prepa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM461251(6-(3-(2-chloro-4-((4- cyclopropyl-1-(2,6-dichloro-...)
Affinity DataEC50:  8.60nMAssay Description:Determination of a ligand mediated Gal4 promoter driven transactivation to quantify ligand binding mediated activation of FXR was performed as follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM461252(5-((1S,3S)-3-(2-chloro-4-((5- cyclopropyl-3-(2,6-d...)
Affinity DataEC50:  49nMAssay Description:Determination of a ligand mediated cofactor peptide interaction to quantify ligand binding to the nuclear receptor FXR was performed as follows.Prepa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM461252(5-((1S,3S)-3-(2-chloro-4-((5- cyclopropyl-3-(2,6-d...)
Affinity DataEC50:  353nMAssay Description:Determination of a ligand mediated Gal4 promoter driven transactivation to quantify ligand binding mediated activation of FXR was performed as follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM461253(2-(6-(3-(2-chloro-4-((5- cyclopropyl-3-(2,6-dichlo...)
Affinity DataEC50:  6.90nMAssay Description:Determination of a ligand mediated cofactor peptide interaction to quantify ligand binding to the nuclear receptor FXR was performed as follows.Prepa...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM461253(2-(6-(3-(2-chloro-4-((5- cyclopropyl-3-(2,6-dichlo...)
Affinity DataEC50:  1.70E+3nMAssay Description:Determination of a ligand mediated Gal4 promoter driven transactivation to quantify ligand binding mediated activation of FXR was performed as follow...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM461254((6-(3-(2-chloro-4-((5- cyclopropyl-3-(2,6-dichloro...)
Affinity DataEC50:  8.10nMAssay Description:Determination of a ligand mediated cofactor peptide interaction to quantify ligand binding to the nuclear receptor FXR was performed as follows.Prepa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM461247(2-(3-(2-chloro-4-((5- cyclopropyl-3-(2,4- difluoro...)
Affinity DataEC50:  3.00E+3nMAssay Description:Determination of a ligand mediated Gal4 promoter driven transactivation to quantify ligand binding mediated activation of FXR was performed as follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent