Compile Data Set for Download or QSAR
maximum 50k data
Found 36 Enz. Inhib. hit(s) with all data for entry = 800
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Proximagen

US Patent
LigandPNGBDBM291375(4-[1-(4-Chlorophenyl)-2-(1H- pyrazo1-4-yl)-1H-pyrr...)
Affinity DataIC50: <100nMAssay Description:All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman et a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Proximagen

US Patent
LigandPNGBDBM291376(4-[1-(4-Chlorophenyl)-2-(1- methyl-1H-pyrazol-4-yl...)
Affinity DataIC50: <100nMAssay Description:All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman et a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Proximagen

US Patent
LigandPNGBDBM291367(4-[2-(6-Aminopyridin-3-yl)-1-(4-chlorophenyl)-1H-p...)
Affinity DataIC50: <100nMAssay Description:All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman et a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Proximagen

US Patent
LigandPNGBDBM291378(4-[1-(4-Chlorophenyl)-2-(1- methyl-1H-imidazol-5-y...)
Affinity DataIC50: <100nMAssay Description:All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman et a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Proximagen

US Patent
LigandPNGBDBM291369(4-[1-(4-Chlorophenyl)-2-(6- methoxypyridin-3-yl)-1...)
Affinity DataIC50: <100nMAssay Description:All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman et a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Proximagen

US Patent
LigandPNGBDBM291377(4-[1-(4-Chlorophenyl)-2-(1-methyl-1H-pyrazol-5-yl)...)
Affinity DataIC50: <100nMAssay Description:All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman et a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Proximagen

US Patent
LigandPNGBDBM291370(4-[1-(4-Chlorophenyl)-2-(2- methoxypyridin-4-yl)-1...)
Affinity DataIC50: <100nMAssay Description:All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman et a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Proximagen

US Patent
LigandPNGBDBM291383(4-[1-(4-Chlorophenyl)-3-(piperidin-4-yl)-1H-pyrrol...)
Affinity DataIC50: <100nMAssay Description:All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman et a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Proximagen

US Patent
LigandPNGBDBM291371(4-[1-(4-Chlorophenyl)-2-[2-(4- methylpiperazin-1-y...)
Affinity DataIC50: <100nMAssay Description:All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman et a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Proximagen

US Patent
LigandPNGBDBM291372(4-[1-(4-Chlorophenyl)-2-[6- (morpholin-4-yl)pyridi...)
Affinity DataIC50: <100nMAssay Description:All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman et a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Proximagen

US Patent
LigandPNGBDBM291372(4-[1-(4-Chlorophenyl)-2-[6- (morpholin-4-yl)pyridi...)
Affinity DataIC50:  550nMpH: 7.3 T: 2°CAssay Description:Compounds of the invention were tested for inhibition of the human ether a go-go related gene (hERG) K+ channel using IonWorks patch clamp electrophy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Proximagen

US Patent
LigandPNGBDBM291370(4-[1-(4-Chlorophenyl)-2-(2- methoxypyridin-4-yl)-1...)
Affinity DataIC50:  550nMpH: 7.3 T: 2°CAssay Description:Compounds of the invention were tested for inhibition of the human ether a go-go related gene (hERG) K+ channel using IonWorks patch clamp electrophy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Proximagen

US Patent
LigandPNGBDBM291374(4-[1-(4-Chlorophenyl)-2-(1H- pyrazol-3-yl)-1H-pyrr...)
Affinity DataIC50: <1.00E+3nMAssay Description:All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman et a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Proximagen

US Patent
LigandPNGBDBM291373(4-[1-(4-Chlorophenyl)-2- (pyrimidin-5-yl)-1H-pyrro...)
Affinity DataIC50: <1.00E+3nMAssay Description:All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman et a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Proximagen

US Patent
LigandPNGBDBM291368(4-[1-(4-Chlorophenyl)-2- (pyridin-3-yl)-1H-pyrrolo...)
Affinity DataIC50: <1.00E+3nMAssay Description:All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman et a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Proximagen

US Patent
LigandPNGBDBM291387(4-[1-(4-Chlorophenyl)-2-(2H-1,2,3,4-tetrazol-5-yl)...)
Affinity DataIC50: >1.00E+3nMAssay Description:All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman et a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Proximagen

US Patent
LigandPNGBDBM291386(US9580415, Example 20 | {[1-(4-Chlorophenyl)-2-(py...)
Affinity DataIC50: >1.00E+3nMAssay Description:All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman et a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Proximagen

US Patent
LigandPNGBDBM291385(US9580415, Example 19 | {[1-(4-Chlorophenyl)-2-(py...)
Affinity DataIC50: <1.00E+3nMAssay Description:All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman et a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Proximagen

US Patent
LigandPNGBDBM291384(5-[1-(4-Chlorophenyl)-3-(piperidin-4-yl)-1H-pyrrol...)
Affinity DataIC50: <1.00E+3nMAssay Description:All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman et a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Proximagen

US Patent
LigandPNGBDBM291382(4-[1-(4-Chlorophenyl)-2-(1H- 1,2,4-triazol-1-yl)-1...)
Affinity DataIC50: >1.00E+3nMAssay Description:All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman et a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Proximagen

US Patent
LigandPNGBDBM291381(4-[1-(4-Chlorophenyl)-2-(1H- 1,2,3-triazol-1-yl)-1...)
Affinity DataIC50: >1.00E+3nMAssay Description:All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman et a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Proximagen

US Patent
LigandPNGBDBM291380(4-[1-(4-Chlorophenyl)-2-(1H- imidazol-1-yl)-1H-pyr...)
Affinity DataIC50: <1.00E+3nMAssay Description:All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman et a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Proximagen

US Patent
LigandPNGBDBM291379(4-[1-(4-Chlorophenyl)-2-(1H- pyrazol-1-yl)-1H-pyrr...)
Affinity DataIC50: <1.00E+3nMAssay Description:All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman et a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Proximagen

US Patent
LigandPNGBDBM291385(US9580415, Example 19 | {[1-(4-Chlorophenyl)-2-(py...)
Affinity DataIC50:  5.50E+3nMpH: 7.3 T: 2°CAssay Description:Compounds of the invention were tested for inhibition of the human ether a go-go related gene (hERG) K+ channel using IonWorks patch clamp electrophy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Proximagen

US Patent
LigandPNGBDBM291383(4-[1-(4-Chlorophenyl)-3-(piperidin-4-yl)-1H-pyrrol...)
Affinity DataIC50:  5.50E+3nMpH: 7.3 T: 2°CAssay Description:Compounds of the invention were tested for inhibition of the human ether a go-go related gene (hERG) K+ channel using IonWorks patch clamp electrophy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Proximagen

US Patent
LigandPNGBDBM291374(4-[1-(4-Chlorophenyl)-2-(1H- pyrazol-3-yl)-1H-pyrr...)
Affinity DataIC50:  5.50E+3nMpH: 7.3 T: 2°CAssay Description:Compounds of the invention were tested for inhibition of the human ether a go-go related gene (hERG) K+ channel using IonWorks patch clamp electrophy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Proximagen

US Patent
LigandPNGBDBM291373(4-[1-(4-Chlorophenyl)-2- (pyrimidin-5-yl)-1H-pyrro...)
Affinity DataIC50:  5.50E+3nMpH: 7.3 T: 2°CAssay Description:Compounds of the invention were tested for inhibition of the human ether a go-go related gene (hERG) K+ channel using IonWorks patch clamp electrophy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Proximagen

US Patent
LigandPNGBDBM291377(4-[1-(4-Chlorophenyl)-2-(1-methyl-1H-pyrazol-5-yl)...)
Affinity DataIC50:  5.50E+3nMpH: 7.3 T: 2°CAssay Description:Compounds of the invention were tested for inhibition of the human ether a go-go related gene (hERG) K+ channel using IonWorks patch clamp electrophy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Proximagen

US Patent
LigandPNGBDBM291368(4-[1-(4-Chlorophenyl)-2- (pyridin-3-yl)-1H-pyrrolo...)
Affinity DataIC50:  5.50E+3nMpH: 7.3 T: 2°CAssay Description:Compounds of the invention were tested for inhibition of the human ether a go-go related gene (hERG) K+ channel using IonWorks patch clamp electrophy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Proximagen

US Patent
LigandPNGBDBM291367(4-[2-(6-Aminopyridin-3-yl)-1-(4-chlorophenyl)-1H-p...)
Affinity DataIC50:  5.50E+3nMpH: 7.3 T: 2°CAssay Description:Compounds of the invention were tested for inhibition of the human ether a go-go related gene (hERG) K+ channel using IonWorks patch clamp electrophy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Proximagen

US Patent
LigandPNGBDBM291379(4-[1-(4-Chlorophenyl)-2-(1H- pyrazol-1-yl)-1H-pyrr...)
Affinity DataIC50:  5.50E+3nMpH: 7.3 T: 2°CAssay Description:Compounds of the invention were tested for inhibition of the human ether a go-go related gene (hERG) K+ channel using IonWorks patch clamp electrophy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Proximagen

US Patent
LigandPNGBDBM291378(4-[1-(4-Chlorophenyl)-2-(1- methyl-1H-imidazol-5-y...)
Affinity DataIC50: >1.00E+4nMpH: 7.3 T: 2°CAssay Description:Compounds of the invention were tested for inhibition of the human ether a go-go related gene (hERG) K+ channel using IonWorks patch clamp electrophy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Proximagen

US Patent
LigandPNGBDBM291375(4-[1-(4-Chlorophenyl)-2-(1H- pyrazo1-4-yl)-1H-pyrr...)
Affinity DataIC50: >1.00E+4nMpH: 7.3 T: 2°CAssay Description:Compounds of the invention were tested for inhibition of the human ether a go-go related gene (hERG) K+ channel using IonWorks patch clamp electrophy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Proximagen

US Patent
LigandPNGBDBM291387(4-[1-(4-Chlorophenyl)-2-(2H-1,2,3,4-tetrazol-5-yl)...)
Affinity DataIC50: >1.00E+4nMpH: 7.3 T: 2°CAssay Description:Compounds of the invention were tested for inhibition of the human ether a go-go related gene (hERG) K+ channel using IonWorks patch clamp electrophy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Proximagen

US Patent
LigandPNGBDBM291384(5-[1-(4-Chlorophenyl)-3-(piperidin-4-yl)-1H-pyrrol...)
Affinity DataIC50: >1.00E+4nMpH: 7.3 T: 2°CAssay Description:Compounds of the invention were tested for inhibition of the human ether a go-go related gene (hERG) K+ channel using IonWorks patch clamp electrophy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Proximagen

US Patent
LigandPNGBDBM291380(4-[1-(4-Chlorophenyl)-2-(1H- imidazol-1-yl)-1H-pyr...)
Affinity DataIC50: >1.00E+4nMpH: 7.3 T: 2°CAssay Description:Compounds of the invention were tested for inhibition of the human ether a go-go related gene (hERG) K+ channel using IonWorks patch clamp electrophy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent