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Found 18 Enz. Inhib. hit(s) with all data for entry = 2027
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM350906(3-Phenyl-2-(2-naphthylmethylthio)-4-oxo-3,4-dihydr...)
Affinity DataIC50:  90nMAssay Description:Measurement of PDE7 inhibition was carried out using a commercial phosphodiesterase activity measurement kit.Some of the compounds of the present inv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM350888(3-Phenyl-2-neopentylthio-4-oxo-3,4-dihydroquinazol...)
Affinity DataIC50:  100nMAssay Description:Measurement of PDE7 inhibition was carried out using a commercial phosphodiesterase activity measurement kit.Some of the compounds of the present inv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM350903(3-(2-Methylphenyl)-2-(3-pyridylmethylthio)-4-oxo-3...)
Affinity DataIC50:  120nMAssay Description:Measurement of PDE7 inhibition was carried out using a commercial phosphodiesterase activity measurement kit.Some of the compounds of the present inv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM350886(2-Cyclohexylmethylthio-3-phenyl-4-oxo-3,4-dihydroq...)
Affinity DataIC50:  200nMAssay Description:Measurement of PDE7 inhibition was carried out using a commercial phosphodiesterase activity measurement kit.Some of the compounds of the present inv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM350902(8-Chloro-2-(3-pyridylmethylthio)-4-oxo-3,4-dihydro...)
Affinity DataIC50:  540nMAssay Description:Measurement of PDE7 inhibition was carried out using a commercial phosphodiesterase activity measurement kit.Some of the compounds of the present inv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM350899(2-Benzylthio-3-phenyl-4-oxo-3,4-dihydroquinazoline...)
Affinity DataIC50:  600nMAssay Description:Measurement of PDE7 inhibition was carried out using a commercial phosphodiesterase activity measurement kit.Some of the compounds of the present inv...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM350901(3-Phenyl-2-(3-pyridylmethylthio)-4-oxo-3,4-dihydro...)
Affinity DataIC50:  700nMAssay Description:Measurement of PDE7 inhibition was carried out using a commercial phosphodiesterase activity measurement kit.Some of the compounds of the present inv...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM350900(3-Phenyl-2-(2-pyridylmethylthio)-4-oxo-3,4-dihydro...)
Affinity DataIC50:  800nMAssay Description:Measurement of PDE7 inhibition was carried out using a commercial phosphodiesterase activity measurement kit.Some of the compounds of the present inv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM350890(8-Chloro-3-phenyl-2-neopentylthio-4-oxo-3,4-dihydr...)
Affinity DataIC50:  1.20E+3nMAssay Description:Measurement of PDE7 inhibition was carried out using a commercial phosphodiesterase activity measurement kit.Some of the compounds of the present inv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM350891(3-(2-Methylphenyl)-2-neopentylthio-4-oxo-3,4-dihyd...)
Affinity DataIC50:  1.85E+3nMAssay Description:Measurement of PDE7 inhibition was carried out using a commercial phosphodiesterase activity measurement kit.Some of the compounds of the present inv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM350887(3-(2-Bromophenyl)-2-cyclohexylmethylthio-4-oxo-3,4...)
Affinity DataIC50:  2.11E+3nMAssay Description:Measurement of PDE7 inhibition was carried out using a commercial phosphodiesterase activity measurement kit.Some of the compounds of the present inv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM350898(8-Chloro-2-ethylthio-3-(2,6-difluorophenyl)-4-oxo-...)
Affinity DataIC50:  2.44E+3nMAssay Description:Measurement of PDE7 inhibition was carried out using a commercial phosphodiesterase activity measurement kit.Some of the compounds of the present inv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM350904(3-Phenyl-2-(4-pyridylmethylthio)-4-oxo-3,4-dihydro...)
Affinity DataIC50:  2.60E+3nMAssay Description:Measurement of PDE7 inhibition was carried out using a commercial phosphodiesterase activity measurement kit.Some of the compounds of the present inv...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM350893(2-Cyclopropylmethylthio-3-(2,6-difluorophenyl)-8-m...)
Affinity DataIC50:  4.56E+3nMAssay Description:Measurement of PDE7 inhibition was carried out using a commercial phosphodiesterase activity measurement kit.Some of the compounds of the present inv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM350894(2-Ethylthio-3-phenyl-4-oxo-3,4-dihydroquinazoline ...)
Affinity DataIC50:  6.90E+3nMAssay Description:Measurement of PDE7 inhibition was carried out using a commercial phosphodiesterase activity measurement kit.Some of the compounds of the present inv...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM350895(2-Ethylthio-3-(2,6-difluorophenyl)-4-oxo-3,4-dihyd...)
Affinity DataIC50:  6.99E+3nMAssay Description:Measurement of PDE7 inhibition was carried out using a commercial phosphodiesterase activity measurement kit.Some of the compounds of the present inv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM350889(3-(2,6-Difluorophenyl)-8-methyl-2-neopentylthio-4-...)
Affinity DataIC50:  8.67E+3nMAssay Description:Measurement of PDE7 inhibition was carried out using a commercial phosphodiesterase activity measurement kit.Some of the compounds of the present inv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM350892(3-(2-Bromophenyl)-2-cyclopropylmethylthio-4-oxo-3,...)
Affinity DataIC50:  9.44E+3nMAssay Description:Measurement of PDE7 inhibition was carried out using a commercial phosphodiesterase activity measurement kit.Some of the compounds of the present inv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent