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Found 4 Enz. Inhib. hit(s) for PDB: 2CGF
TargetATP-dependent molecular chaperone HSP82(Saccharomyces cerevisiae)
University Of Nottingham

LigandPNGBDBM68248(Microlactone, 15a)
Affinity DataIC50:  100nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
TargetATP-dependent molecular chaperone HSP82(Saccharomyces cerevisiae)
University Of Nottingham

LigandPNGBDBM68248(Microlactone, 15a)
Affinity DataIC50:  120nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
TargetATP-dependent molecular chaperone HSP82(Saccharomyces cerevisiae)
University Of Nottingham

LigandPNGBDBM68248(Microlactone, 15a)
Affinity DataIC50: <1.00E+3nMAssay Description:A colorimetric assay for the release of inorganic phosphate upon hydrolysis of ATP was used to determine the potency of Hsp 90 inhibitor against enzy...More data for this Ligand-Target Pair
TargetATP-dependent molecular chaperone HSP82(Saccharomyces cerevisiae)
University Of Nottingham

LigandPNGBDBM68248(Microlactone, 15a)
Affinity DataIC50:  1.30E+3nMAssay Description:A colorimetric assay for the release of inorganic phosphate upon hydrolysis of ATP was used to determine the potency of Hsp 90 inhibitor against enzy...More data for this Ligand-Target Pair