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Found 1 Enz. Inhib. hit(s) for PDB: 3FRJ
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

LigandPNGBDBM28376(N-{1-[(1-carbamoylcyclopropyl)methyl]piperidin-4-y...)
Affinity DataIC50:  14nMpH: 7.5 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair