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Compile Data Set for Download or QSAR
maximum 50k data
Found
1
Enz. Inhib. hit(s) for PDB:
3FRJ
Target
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human))
Amgen
Ligand
BDBM28376
(N-{1-[(1-carbamoylcyclopropyl)methyl]piperidin-4-y...)
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Affinity Data
IC50: 14nM
pH: 7.5 T: 2°C
Assay Description:
Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...
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