Found 22 Enz. Inhib. hit(s) for PDB: 3RJW 
Affinity DataKi: 3.70nMAssay Description:Competitive inhibition of G9a by fluorescence polarization assay in presence of fluorescein-labeled H3 peptideMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKi: 3.70nMAssay Description:Competitive inhibition of G9a (unknown origin) by Morrison plot analysis in presence of histone H3 (1 to 25 residues)More data for this Ligand-Target Pair
Affinity DataKi: 570nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibition of G9a (unknown origin) using [histone H3 1 to 25 residues] and SAM substrate by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of G9a assessed as hydrolysis of S-adenosyl-L-homocysteine after 2 mins by SAHH-coupled fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: <15nMAssay Description:Inhibition of EHMT2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: <15nMAssay Description:Inhibition of G9a (unknown origin) using histone H3 (1 to 25 residues) as substrate preincubated for 2 mins followed by substrate addition measured f...More data for this Ligand-Target Pair
Affinity DataIC50: <15nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of G9a in human 22Rv1 cells assessed as reduction of H3K9me2 after 48 hrs by In-Cell Western assayMore data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Inhibition of human G9a using biotinylated-H3K9 peptide as substrate after 1 hr in presence of SAM by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Inhibition of human G9a using biotinylated-H3K9 peptide as substrate after 1 hr in presence of SAM by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 59nMAssay Description:Inhibition of G9a in human PC3 cells assessed as reduction of H3K9me2 after 48 hrs by In-Cell Western assayMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of G9a in human MCF7 cells assessed as reduction of H3K9me2 after 48 hrs by In-Cell Western assayMore data for this Ligand-Target Pair
Affinity DataIC50: 81nMAssay Description:Inhibition of lysine methyltransferase G9a in human MDA-MB-231 cells assessed as reduction of H3K9me2 cellular level by immunofluorescence in-cell We...More data for this Ligand-Target Pair
Affinity DataIC50: 81nMAssay Description:Inhibition of G9a in human MDA-MB-231 cells after 48 hrs by clonogenic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 81nMAssay Description:Inhibition of G9a in human MDA-MB-231 cells assessed as reduction of H3K9me2 after 48 hrs by In-Cell Western assayMore data for this Ligand-Target Pair
Affinity DataIC50: 81nMAssay Description:Inhibition of G9a in human MDA-MB-231 cells assessed as reduction of H3K9me2 after 48 hrs by In-Cell Western assayMore data for this Ligand-Target Pair
Affinity DataIC50: 81nMAssay Description:Inhibition of G9a in human MCF7 cells after 48 hrs by clonogenic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of G9a in human IMR90 cells assessed as reduction of H3K9me2 after 48 hrs by In-Cell Western assayMore data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inhibition of G9a in human HCT116 cells assessed as reduction of H3K9me2 after 48 hrs by In-Cell Western assayMore data for this Ligand-Target Pair
Affinity DataIC50: 610nMAssay Description:Inhibition of G9a (unknown origin) using biotinylated-histone H3 (1 to 21 residues)/S-adenosyl-methionine as substrate/methyl donor after 3 hrs by Al...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of G9a (unknown origin) by HMT assayMore data for this Ligand-Target Pair
