Found 5 Enz. Inhib. hit(s) for PDB: 3U9N 
Affinity DataIC50: 75nMAssay Description:Inhibition of recombinant His-tagged CHK1 using biotin-RSGLYRSPSMPENLNRPR as substrate after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 75nMAssay Description:Inhibition of recombinant His-tagged CHK1 (unknown origin) expressed in baculovirus expression system using biotin-RSGLYRSPSMPENLNRPR as substrate af...More data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+4nMAssay Description:Inhibition of CHK1 in human U2OS cells assessed as phosphorylation of H2AX after 2 hrs by FITC/propidium iodide staining-based immunofluorescence ass...More data for this Ligand-Target Pair
Affinity DataKd: <100nMAssay Description:Binding affinity to CHK1 by affinity-selection-mass spectrophotometry assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+4nMAssay Description:Inhibition of CHK1 in human U2OS cells pretreated with hydroxyurea assessed as gamma-H2AX level after 2 hrs by immunofluorescence assayMore data for this Ligand-Target Pair
