Compile Data Set for Download or QSAR
maximum 50k data
Found 16 Enz. Inhib. hit(s) with all data for entry = 50017758
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Arpida

Curated by ChEMBL
LigandPNGBDBM50186088((S)-2-amino-N-((S)-2-(biphenyl-4-yl)-1-cyanoethyl)...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human DPP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Arpida

Curated by ChEMBL
LigandPNGBDBM50186090((S)-2-amino-N-((S)-2-(4-chlorophenyl)-1-cyanoethyl...)
Affinity DataIC50:  96nMAssay Description:Inhibition of human DPP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Arpida

Curated by ChEMBL
LigandPNGBDBM50186089((S)-2-amino-N-((S,E)-1-cyano-4-phenylbut-3-enyl)bu...)
Affinity DataIC50:  137nMAssay Description:Inhibition of human DPP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Arpida

Curated by ChEMBL
LigandPNGBDBM50186091((S)-2-amino-N-((S)-1-cyano-2-phenylethyl)butanamid...)
Affinity DataIC50:  172nMAssay Description:Inhibition of human DPP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Arpida

Curated by ChEMBL
LigandPNGBDBM50186093((S)-2-amino-N-((S)-1-cyano-3-phenylpropyl)butanami...)
Affinity DataIC50:  822nMAssay Description:Inhibition of human DPP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Arpida

Curated by ChEMBL
LigandPNGBDBM50186088((S)-2-amino-N-((S)-2-(biphenyl-4-yl)-1-cyanoethyl)...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Arpida

Curated by ChEMBL
LigandPNGBDBM50186094((S)-2-amino-N-(1-cyano-2-phenylethyl)acetamide | C...)
Affinity DataIC50:  4.79E+3nMAssay Description:Inhibition of human DPP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Arpida

Curated by ChEMBL
LigandPNGBDBM50186087((2S)-2-amino-N-(1-cyano-2-phenylethyl)-3-phenylpro...)
Affinity DataIC50:  6.29E+3nMAssay Description:Inhibition of human DPP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Arpida

Curated by ChEMBL
LigandPNGBDBM50186092((S)-N-((S)-1-cyano-2-phenylethyl)pyrrolidine-2-car...)
Affinity DataIC50:  9.64E+3nMAssay Description:Inhibition of human DPP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPro-cathepsin H(Homo sapiens (Human))
Arpida

Curated by ChEMBL
LigandPNGBDBM50186088((S)-2-amino-N-((S)-2-(biphenyl-4-yl)-1-cyanoethyl)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Cathepsin HMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Arpida

Curated by ChEMBL
LigandPNGBDBM50186088((S)-2-amino-N-((S)-2-(biphenyl-4-yl)-1-cyanoethyl)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Arpida

Curated by ChEMBL
LigandPNGBDBM50186088((S)-2-amino-N-((S)-2-(biphenyl-4-yl)-1-cyanoethyl)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Arpida

Curated by ChEMBL
LigandPNGBDBM50186088((S)-2-amino-N-((S)-2-(biphenyl-4-yl)-1-cyanoethyl)...)
Affinity DataIC50:  1.26E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Arpida

Curated by ChEMBL
LigandPNGBDBM50186088((S)-2-amino-N-((S)-2-(biphenyl-4-yl)-1-cyanoethyl)...)
Affinity DataIC50:  1.49E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Arpida

Curated by ChEMBL
LigandPNGBDBM50186088((S)-2-amino-N-((S)-2-(biphenyl-4-yl)-1-cyanoethyl)...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Arpida

Curated by ChEMBL
LigandPNGBDBM50186088((S)-2-amino-N-((S)-2-(biphenyl-4-yl)-1-cyanoethyl)...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed