Compile Data Set for Download or QSAR
maximum 50k data
Found 55 Enz. Inhib. hit(s) with all data for entry = 50042825
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431696(CHEMBL2349534)
Affinity DataIC50:  1.10nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431690(CHEMBL2349540)
Affinity DataIC50:  2.30nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431692(CHEMBL2349538)
Affinity DataIC50:  3.70nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431695(CHEMBL2349535)
Affinity DataIC50:  3.80nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431693(CHEMBL2349537)
Affinity DataIC50:  4.30nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431697(CHEMBL2349533)
Affinity DataIC50:  4.40nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431694(CHEMBL2349536)
Affinity DataIC50:  4.70nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431691(CHEMBL2349539)
Affinity DataIC50:  5.30nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431689(CHEMBL2349541)
Affinity DataIC50:  5.30nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431717(CHEMBL2346726)
Affinity DataIC50:  5.80nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431722(CHEMBL2346721)
Affinity DataIC50:  7.10nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431728(CHEMBL2346715)
Affinity DataIC50:  10nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431719(CHEMBL2346724 | MTE)
Affinity DataIC50:  12nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50122758(2-methyl-4-(pyridin-3-ylethynyl)thiazole | 3-(2-(2...)
Affinity DataIC50:  12nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431718(CHEMBL2346725)
Affinity DataIC50:  13nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431716(CHEMBL2346727)
Affinity DataIC50:  15nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431721(CHEMBL2346722)
Affinity DataIC50:  16nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431678(CHEMBL2346711)
Affinity DataIC50:  16nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431687(CHEMBL2349543)
Affinity DataIC50:  17nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431713(CHEMBL2346730)
Affinity DataIC50:  17nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431705(ADX48621 | CHEMBL2346738 | Dipraglurant)
Affinity DataIC50:  20nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431712(CHEMBL2346731)
Affinity DataIC50:  24nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431684(CHEMBL2349546)
Affinity DataIC50:  25nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431704(CHEMBL2346739)
Affinity DataIC50:  27nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431701(CHEMBL2349529)
Affinity DataIC50:  27nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431730(CHEMBL2346713)
Affinity DataIC50:  28nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431688(CHEMBL2349542)
Affinity DataIC50:  38nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431706(CHEMBL2346737)
Affinity DataIC50:  40nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431723(CHEMBL2346720)
Affinity DataIC50:  42nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431714(CHEMBL2346729)
Affinity DataIC50:  46nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431724(CHEMBL2346719)
Affinity DataIC50:  56nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431708(CHEMBL2346735)
Affinity DataIC50:  62nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431702(CHEMBL2349528)
Affinity DataIC50:  63nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431685(CHEMBL2349545)
Affinity DataIC50:  71nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431710(CHEMBL2346733)
Affinity DataIC50:  77nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431679(CHEMBL2349553)
Affinity DataIC50:  82nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431707(CHEMBL2346736)
Affinity DataIC50:  88nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431680(CHEMBL2349552)
Affinity DataIC50:  91nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431683(CHEMBL2349547)
Affinity DataIC50:  92nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431698(CHEMBL2349532)
Affinity DataIC50:  95nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431725(CHEMBL2346718)
Affinity DataIC50:  95nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431677(CHEMBL2346712)
Affinity DataIC50:  130nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431709(CHEMBL2346734)
Affinity DataIC50:  139nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431715(CHEMBL2346728)
Affinity DataIC50:  147nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431711(CHEMBL2346732)
Affinity DataIC50:  173nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431727(CHEMBL2346716)
Affinity DataIC50:  184nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431729(CHEMBL2346714)
Affinity DataIC50:  195nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431726(CHEMBL2346717)
Affinity DataIC50:  301nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431703(CHEMBL2349527)
Affinity DataIC50:  373nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431686(CHEMBL2349544)
Affinity DataIC50:  645nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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