Compile Data Set for Download or QSAR
maximum 50k data
Found 13 Enz. Inhib. hit(s) with all data for entry = 50005870
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Praecis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50158348((2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihy...)
Affinity DataEC50:  3.90nMAssay Description:Agonist activity at human S1P3R expressed in HEK293T cells assessed as [35S]GTPgammaS binding after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 2(Homo sapiens (Human))
Praecis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50158348((2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihy...)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at human S1P2R expressed in HEK293T cells assessed as [35S]GTPgammaS binding after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Praecis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50495089(CHEMBL3102904)
Affinity DataEC50:  0.260nMAssay Description:Agonist activity at human S1P1R expressed in HEK293T cells assessed as [35S]GTPgammaS binding after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Praecis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50495090(CHEMBL3102903)
Affinity DataEC50:  0.440nMAssay Description:Agonist activity at human S1P1R expressed in HEK293T cells assessed as [35S]GTPgammaS binding after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Praecis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50495090(CHEMBL3102903)
Affinity DataEC50:  2nMAssay Description:Agonist activity at human S1P5R expressed in HEK293T cells assessed as [35S]GTPgammaS binding after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Praecis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50158348((2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihy...)
Affinity DataEC50:  4.30nMAssay Description:Agonist activity at human S1P1R expressed in HEK293T cells assessed as [35S]GTPgammaS binding after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 4(Homo sapiens (Human))
Praecis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50158348((2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihy...)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human S1P4R expressed in HEK293T cells assessed as [35S]GTPgammaS binding after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 4(Homo sapiens (Human))
Praecis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50495089(CHEMBL3102904)
Affinity DataEC50:  4.60nMAssay Description:Agonist activity at human S1P4R expressed in HEK293T cells assessed as [35S]GTPgammaS binding after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 4(Homo sapiens (Human))
Praecis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50495090(CHEMBL3102903)
Affinity DataEC50:  3.60nMAssay Description:Agonist activity at human S1P4R expressed in HEK293T cells assessed as [35S]GTPgammaS binding after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Praecis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50495090(CHEMBL3102903)
Affinity DataEC50: >3.00E+3nMAssay Description:Agonist activity at human S1P3R expressed in HEK293T cells assessed as [35S]GTPgammaS binding after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Praecis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50495089(CHEMBL3102904)
Affinity DataEC50:  0.660nMAssay Description:Agonist activity at human S1P5R expressed in HEK293T cells assessed as [35S]GTPgammaS binding after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Praecis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50495089(CHEMBL3102904)
Affinity DataEC50: >3.00E+3nMAssay Description:Agonist activity at human S1P3R expressed in HEK293T cells assessed as [35S]GTPgammaS binding after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Praecis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50158348((2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihy...)
Affinity DataEC50:  1.80nMAssay Description:Agonist activity at human S1P5R expressed in HEK293T cells assessed as [35S]GTPgammaS binding after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed