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Found 9 Enz. Inhib. hit(s) with all data for entry = 50047187
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Waterloo

Curated by ChEMBL
LigandPNGBDBM50152733(CHEMBL3781564)
Affinity DataIC50:  300nMAssay Description:Inhibition of human AChE assessed as hydrolytic activity using acetylthiocholine iodide as substrate measured for 15 mins by Ellmans assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Waterloo

Curated by ChEMBL
LigandPNGBDBM50152733(CHEMBL3781564)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of human BuChE assessed as hydrolytic activity using butyrylthiocholine iodide as substrate measured for 15 mins by Ellmans assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Waterloo

Curated by ChEMBL
LigandPNGBDBM50152738(CHEMBL3781022)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of amyloid beta (1 to 42) (unknown origin) aggregation measured after 24 hrs by Thioflavin T-based fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Waterloo

Curated by ChEMBL
LigandPNGBDBM50152737(CHEMBL3781419)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibition of amyloid beta (1 to 42) (unknown origin) aggregation measured after 24 hrs by Thioflavin T-based fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Waterloo

Curated by ChEMBL
LigandPNGBDBM50152739(CHEMBL3781026)
Affinity DataIC50:  4.05E+4nMAssay Description:Inhibition of amyloid beta (1 to 42) (unknown origin) aggregation measured after 24 hrs by Thioflavin T-based fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Waterloo

Curated by ChEMBL
LigandPNGBDBM50152735(CHEMBL3780448)
Affinity DataIC50:  8.08E+4nMAssay Description:Inhibition of human AChE assessed as hydrolytic activity using acetylthiocholine iodide as substrate measured for 15 mins by Ellmans assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Waterloo

Curated by ChEMBL
LigandPNGBDBM50152736(CHEMBL3780131)
Affinity DataIC50:  1.11E+5nMAssay Description:Inhibition of human AChE assessed as hydrolytic activity using acetylthiocholine iodide as substrate measured for 15 mins by Ellmans assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Waterloo

Curated by ChEMBL
LigandPNGBDBM50152735(CHEMBL3780448)
Affinity DataIC50:  1.64E+5nMAssay Description:Inhibition of human BuChE assessed as hydrolytic activity using butyrylthiocholine iodide as substrate measured for 15 mins by Ellmans assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Waterloo

Curated by ChEMBL
LigandPNGBDBM50152736(CHEMBL3780131)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of human BuChE assessed as hydrolytic activity using butyrylthiocholine iodide as substrate measured for 15 mins by Ellmans assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed