Compile Data Set for Download or QSAR
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Found 4 Enz. Inhib. hit(s) with all data for entry = 7619
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM206291(4-((2-((3-(Tert-butyl)phenyl)amino)quinolin-5-yl)o...)
Affinity DataIC50:  9.26E+4nMpH: 7.5 T: 2°CAssay Description:Reaction Biology Corporation Kinase HotSpotSM service: In a final reactionvolume of 25 μL, kinase (5-10 mU) is incubated with 25 mM Tris pH 7.5,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM206292(4-((2-((4-Chloro-3-(trifluoromethyl)phenyl)amino)q...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:Reaction Biology Corporation Kinase HotSpotSM service: In a final reactionvolume of 25 μL, kinase (5-10 mU) is incubated with 25 mM Tris pH 7.5,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM206291(4-((2-((3-(Tert-butyl)phenyl)amino)quinolin-5-yl)o...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:Reaction Biology Corporation Kinase HotSpotSM service: In a final reactionvolume of 25 μL, kinase (5-10 mU) is incubated with 25 mM Tris pH 7.5,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Korea Institute Of Science And Technology

LigandPNGBDBM206292(4-((2-((4-Chloro-3-(trifluoromethyl)phenyl)amino)q...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:Reaction Biology Corporation Kinase HotSpotSM service: In a final reactionvolume of 25 μL, kinase (5-10 mU) is incubated with 25 mM Tris pH 7.5,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed