Compile Data Set for Download or QSAR
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Found 6 Enz. Inhib. hit(s) with all data for entry = 50001128
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50269785(CHEMBL4064645)
Affinity DataIC50:  15nMAssay Description:Inhibition of recombinant human 5alpha-reductase type2 expressed in baculovirus expression system using [7-3H]T as substrate pretreated for 18 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50269785(CHEMBL4064645)
Affinity DataIC50:  410nMAssay Description:Inhibition of recombinant human 5alpha-reductase type1 expressed in baculovirus expression system using [7-3H]T as substrate pretreated for 18 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50269786(CHEMBL4076351)
Affinity DataIC50:  1.68E+4nMAssay Description:Displacement of fluormone-AL Green from recombinant rat His-tagged/GST-fused androgen receptor LBD expressed in baculovirus expression system measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50423551(MESTEROLONE | SH-723)
Affinity DataIC50:  1.83E+4nMAssay Description:Displacement of fluormone-AL Green from recombinant rat His-tagged/GST-fused androgen receptor LBD expressed in baculovirus expression system measure...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50269785(CHEMBL4064645)
Affinity DataIC50:  2.30E+4nMAssay Description:Displacement of [3H]-DHT from recombinant human androgen receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50269787(CHEMBL4061869)
Affinity DataIC50:  4.76E+4nMAssay Description:Displacement of fluormone-AL Green from recombinant rat His-tagged/GST-fused androgen receptor LBD expressed in baculovirus expression system measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed