Found 30 Enz. Inhib. hit(s) with all data for entry = 50001346 
Affinity DataKi: 0.5nMAssay Description:Binding affinity to ERalpha (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Binding affinity to ERbeta (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of [125I]2-(3'-Iodo-4'-N-methylaminophenyl) benzothiazole binding to amyloid beta (1 to 40) (unknown origin) after 3 hrs by NaI well count...More data for this Ligand-Target Pair
Affinity DataKi: 3.70nMAssay Description:Antagonist activity at ER in human Ishikawa cells assessed as inhibition of E2-induced alkaline phosphatase induction after 72 hrs by PNPP substrate ...More data for this Ligand-Target Pair
Affinity DataKi: 4.30nMAssay Description:Antagonist activity at ER in human MCF7 cells assessed as inhibition of 17beta-estradiol-induced cell proliferationMore data for this Ligand-Target Pair
Affinity DataKi: 4.31nMAssay Description:Inhibition of [125I]2-(3'-Iodo-4'-N-methylaminophenyl) benzothiazole binding to amyloid beta (1 to 40) (unknown origin) after 3 hrs by NaI well count...More data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Inhibition of human erythrocytes mu-calpain using SucLeu-Tyr-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 1.18E+4nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 5.98E+4nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 3.41E+5nMAssay Description:Inhibition of BuChE (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 4.89E+6nMAssay Description:Inhibition of BuChE (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: <0.00200nMAssay Description:Displacement of [3H]17beta-estradiol from ER in human MCF7 cells after 18 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0460nMAssay Description:Displacement of [3H]17beta-estradiol from ER in human MCF7 cells after 18 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibition of [125I]2-(3'-Iodo-4'-N-methylaminophenyl) benzothiazole binding to amyloid beta (1 to 42) (unknown origin) after 3 hrs by NaI well count...More data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Inhibition of human placental aldose reductase using glyceraldehyde as substrate in presence of NADPHMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 14nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 53nMAssay Description:Inhibition of [125I]2-(3'-Iodo-4'-N-methylaminophenyl) benzothiazole binding to amyloid beta (1 to 42) (unknown origin) after 3 hrs by NaI well count...More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of human placental aldose reductase using glyceraldehyde as substrate in presence of NADPHMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of human placental aldose reductase using glyceraldehyde as substrate in presence of NADPHMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Jain University
Curated by ChEMBL
Jain University
Curated by ChEMBL
Affinity DataIC50: 201nMAssay Description:Antagonist activity at human GABA-A alpha5 receptor expressed in HEK293 cell membranes assessed as inhibition of GABA-induced response preincubated f...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Jain University
Curated by ChEMBL
Jain University
Curated by ChEMBL
Affinity DataIC50: 479nMAssay Description:Antagonist activity at human GABA-A alpha1 receptor expressed in HEK293 cell membranes assessed as inhibition of GABA-induced response preincubated f...More data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.14E+3nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.22E+4nMAssay Description:Inhibition of COX2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.45E+4nMAssay Description:Inhibition of COX2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.45E+4nMAssay Description:Inhibition of COX2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.77E+4nMAssay Description:Inhibition of COX2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 0.900nMAssay Description:Agonist activity at ER in human Ishikawa cells assessed as alkaline phosphatase induction after 72 hrs by PNPP substrate based spectophotometric meth...More data for this Ligand-Target Pair
