Compile Data Set for Download or QSAR
maximum 50k data
Found 45 Enz. Inhib. hit(s) with all data for entry = 50007062
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505835(CHEMBL4463643)
Affinity DataIC50:  200nMAssay Description:Inhibition of human topoisomerase 2alpha mediated decatenation using kDNA as susbtrate preincubated for 20 mins followed by substrate and ATP additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505828(CHEMBL4527023)
Affinity DataIC50:  600nMAssay Description:Inhibition of human topoisomerase 2alpha mediated decatenation using kDNA as susbtrate preincubated for 20 mins followed by substrate and ATP additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505826(CHEMBL4552030)
Affinity DataIC50:  700nMAssay Description:Inhibition of human topoisomerase 2alpha mediated decatenation using kDNA as susbtrate preincubated for 20 mins followed by substrate and ATP additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505828(CHEMBL4527023)
Affinity DataIC50:  700nMAssay Description:Inhibition of topoisomerase 2alpha dependent TCF transcription in human SW620 organoids transduced with TOPflash luminescent reporter after 72 hrs by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505835(CHEMBL4463643)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of topoisomerase 2alpha dependent TCF transcription in human SW620 organoids transduced with TOPflash luminescent reporter after 72 hrs by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505831(CHEMBL4454056)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of topoisomerase 2alpha dependent TCF transcription in human SW620 organoids transduced with TOPflash luminescent reporter after 72 hrs by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505821(CHEMBL4457343)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human topoisomerase 2alpha mediated decatenation using kDNA as susbtrate preincubated for 20 mins followed by substrate and ATP additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505822(CHEMBL4514715)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human topoisomerase 2alpha mediated decatenation using kDNA as susbtrate preincubated for 20 mins followed by substrate and ATP additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505823(CHEMBL4584155)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of topoisomerase 2alpha dependent TCF transcription in human SW620 organoids transduced with TOPflash luminescent reporter after 72 hrs by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505832(CHEMBL4462930)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of human topoisomerase 2alpha mediated decatenation using kDNA as susbtrate preincubated for 20 mins followed by substrate and ATP additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505832(CHEMBL4462930)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of topoisomerase 2alpha dependent TCF transcription in human SW620 organoids transduced with TOPflash luminescent reporter after 72 hrs by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505833(CHEMBL4564777)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of human topoisomerase 2alpha mediated decatenation using kDNA as susbtrate preincubated for 20 mins followed by substrate and ATP additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505821(CHEMBL4457343)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of topoisomerase 2alpha dependent TCF transcription in human SW620 organoids transduced with TOPflash luminescent reporter after 72 hrs by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505824(CHEMBL4476462)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of topoisomerase 2alpha dependent TCF transcription in human SW620 organoids transduced with TOPflash luminescent reporter after 72 hrs by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505830(CHEMBL4474912)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of topoisomerase 2alpha dependent TCF transcription in human SW620 organoids transduced with TOPflash luminescent reporter after 72 hrs by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505825(CHEMBL4559962)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of human topoisomerase 2alpha mediated decatenation using kDNA as susbtrate preincubated for 20 mins followed by substrate and ATP additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505830(CHEMBL4474912)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of human topoisomerase 2alpha mediated decatenation using kDNA as susbtrate preincubated for 20 mins followed by substrate and ATP additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505822(CHEMBL4514715)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of topoisomerase 2alpha dependent TCF transcription in human SW620 organoids transduced with TOPflash luminescent reporter after 72 hrs by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505829(CHEMBL4547004)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human topoisomerase 2alpha mediated decatenation using kDNA as susbtrate preincubated for 20 mins followed by substrate and ATP additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505833(CHEMBL4564777)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of topoisomerase 2alpha dependent TCF transcription in human SW620 organoids transduced with TOPflash luminescent reporter after 72 hrs by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505831(CHEMBL4454056)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human topoisomerase 2alpha mediated decatenation using kDNA as susbtrate preincubated for 20 mins followed by substrate and ATP additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505824(CHEMBL4476462)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of human topoisomerase 2alpha mediated decatenation using kDNA as susbtrate preincubated for 20 mins followed by substrate and ATP additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505823(CHEMBL4584155)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of human topoisomerase 2alpha mediated decatenation using kDNA as susbtrate preincubated for 20 mins followed by substrate and ATP additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505834(CHEMBL4467606)
Affinity DataIC50:  7.80E+3nMAssay Description:Inhibition of human topoisomerase 2alpha mediated decatenation using kDNA as susbtrate preincubated for 20 mins followed by substrate and ATP additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505827(CHEMBL4575568)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of human topoisomerase 2alpha mediated decatenation using kDNA as susbtrate preincubated for 20 mins followed by substrate and ATP additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505835(CHEMBL4463643)
Affinity DataEC50:  5.40E+3nMAssay Description:Inhibition of topoisomerase 2alpha in human SW620 organoids transfected with EcadPro-RFP reporter assessed as reversion of epithelial-mesenchymal tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505831(CHEMBL4454056)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of topoisomerase 2alpha in human SW620 organoids transfected with VimPro-GFP reporter assessed as reversion of epithelial-mesenchymal tran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505835(CHEMBL4463643)
Affinity DataEC50:  3.50E+3nMAssay Description:Inhibition of topoisomerase 2alpha in human SW620 organoids transfected with VimPro-GFP reporter assessed as reversion of epithelial-mesenchymal tran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505821(CHEMBL4457343)
Affinity DataEC50:  4.00E+3nMAssay Description:Inhibition of topoisomerase 2alpha in human SW620 organoids transfected with VimPro-GFP reporter assessed as reversion of epithelial-mesenchymal tran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505832(CHEMBL4462930)
Affinity DataEC50:  5.50E+3nMAssay Description:Inhibition of topoisomerase 2alpha in human SW620 organoids transfected with EcadPro-RFP reporter assessed as reversion of epithelial-mesenchymal tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505830(CHEMBL4474912)
Affinity DataEC50:  3.00E+3nMAssay Description:Inhibition of topoisomerase 2alpha in human SW620 organoids transfected with EcadPro-RFP reporter assessed as reversion of epithelial-mesenchymal tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505824(CHEMBL4476462)
Affinity DataEC50:  1.60E+3nMAssay Description:Inhibition of topoisomerase 2alpha in human SW620 organoids transfected with EcadPro-RFP reporter assessed as reversion of epithelial-mesenchymal tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505833(CHEMBL4564777)
Affinity DataEC50:  1.10E+3nMAssay Description:Inhibition of topoisomerase 2alpha in human SW620 organoids transfected with EcadPro-RFP reporter assessed as reversion of epithelial-mesenchymal tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505823(CHEMBL4584155)
Affinity DataEC50:  3.40E+3nMAssay Description:Inhibition of topoisomerase 2alpha in human SW620 organoids transfected with EcadPro-RFP reporter assessed as reversion of epithelial-mesenchymal tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505828(CHEMBL4527023)
Affinity DataEC50:  1.20E+3nMAssay Description:Inhibition of topoisomerase 2alpha in human SW620 organoids transfected with EcadPro-RFP reporter assessed as reversion of epithelial-mesenchymal tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505821(CHEMBL4457343)
Affinity DataEC50:  9.00E+3nMAssay Description:Inhibition of topoisomerase 2alpha in human SW620 organoids transfected with EcadPro-RFP reporter assessed as reversion of epithelial-mesenchymal tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505830(CHEMBL4474912)
Affinity DataEC50:  2.40E+3nMAssay Description:Inhibition of topoisomerase 2alpha in human SW620 organoids transfected with VimPro-GFP reporter assessed as reversion of epithelial-mesenchymal tran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505833(CHEMBL4564777)
Affinity DataEC50:  1.20E+3nMAssay Description:Inhibition of topoisomerase 2alpha in human SW620 organoids transfected with VimPro-GFP reporter assessed as reversion of epithelial-mesenchymal tran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505823(CHEMBL4584155)
Affinity DataEC50:  1.70E+3nMAssay Description:Inhibition of topoisomerase 2alpha in human SW620 organoids transfected with VimPro-GFP reporter assessed as reversion of epithelial-mesenchymal tran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505828(CHEMBL4527023)
Affinity DataEC50:  1.90E+3nMAssay Description:Inhibition of topoisomerase 2alpha in human SW620 organoids transfected with VimPro-GFP reporter assessed as reversion of epithelial-mesenchymal tran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505832(CHEMBL4462930)
Affinity DataEC50:  9.50E+3nMAssay Description:Inhibition of topoisomerase 2alpha in human SW620 organoids transfected with VimPro-GFP reporter assessed as reversion of epithelial-mesenchymal tran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505824(CHEMBL4476462)
Affinity DataEC50:  1.20E+3nMAssay Description:Inhibition of topoisomerase 2alpha in human SW620 organoids transfected with VimPro-GFP reporter assessed as reversion of epithelial-mesenchymal tran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505822(CHEMBL4514715)
Affinity DataEC50:  3.10E+3nMAssay Description:Inhibition of topoisomerase 2alpha in human SW620 organoids transfected with EcadPro-RFP reporter assessed as reversion of epithelial-mesenchymal tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505831(CHEMBL4454056)
Affinity DataEC50:  3.30E+3nMAssay Description:Inhibition of topoisomerase 2alpha in human SW620 organoids transfected with EcadPro-RFP reporter assessed as reversion of epithelial-mesenchymal tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50505822(CHEMBL4514715)
Affinity DataEC50:  4.70E+3nMAssay Description:Inhibition of topoisomerase 2alpha in human SW620 organoids transfected with VimPro-GFP reporter assessed as reversion of epithelial-mesenchymal tran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed