Compile Data Set for Download or QSAR
maximum 50k data
Found 50 Enz. Inhib. hit(s) with all data for entry = 50029282
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282962(1-(4-Fluoro-naphthalen-1-yl)-4-[4-(5-fluoro-pyrimi...)
Affinity DataIC50: >1nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor by the displacement of [3H]-spiperone from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282973(4-Fluoro-N-{1-(4-fluoro-naphthalen-1-yl)-4-[4-(5-f...)
Affinity DataIC50: >1nMAssay Description:In vitro binding affinity of the compound towards sigma receptor by the displacement of [3H]-PPP from guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282974(CHEMBL58283 | N-{1-Cyclohexyl-4-[4-(5-fluoro-pyrim...)
Affinity DataIC50: >1nMAssay Description:In vitro binding affinity towards serotonin 5-HT1A receptor by the displacement of [3H]-8-OH-DPAT from rat hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282958(1-Cyclohexyl-4-[4-(5-fluoro-pyrimidin-2-yl)-pipera...)
Affinity DataIC50: >1nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor by the displacement of [3H]-spiperone from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282966(CHEMBL58282 | N-{1-Cyclohexyl-4-[4-(5-fluoro-pyrim...)
Affinity DataIC50: >1nMAssay Description:In vitro binding affinity towards serotonin 5-HT1A receptor by the displacement of [3H]-8-OH-DPAT from rat hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282974(CHEMBL58283 | N-{1-Cyclohexyl-4-[4-(5-fluoro-pyrim...)
Affinity DataIC50: >2nMAssay Description:In vitro binding affinity of the compound towards sigma receptor by the displacement of [3H]-PPP from guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282969(1-Cyclohexyl-4-[4-(5-fluoro-pyrimidin-2-yl)-pipera...)
Affinity DataIC50:  12nMAssay Description:In vitro binding affinity of the compound towards sigma receptor by the displacement of [3H]-PPP from guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282963(5-Fluoro-2-{4-[4-(4-fluoro-phenyl)-butyl]-piperazi...)
Affinity DataIC50:  23nMAssay Description:In vitro binding affinity of the compound towards sigma receptor by the displacement of [3H]-PPP from guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282969(1-Cyclohexyl-4-[4-(5-fluoro-pyrimidin-2-yl)-pipera...)
Affinity DataIC50:  30nMAssay Description:In vitro binding affinity towards serotonin 5-HT1A receptor by the displacement of [3H]-8-OH-DPAT from rat hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282972(5-Fluoro-2-{4-[3-(4-fluoro-benzenesulfonyl)-propyl...)
Affinity DataIC50: >45nMAssay Description:In vitro binding affinity of the compound towards sigma receptor by the displacement of [3H]-PPP from guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282970(2-(4-Fluoro-phenyl)-5-[4-(5-fluoro-pyrimidin-2-yl)...)
Affinity DataIC50:  46nMAssay Description:In vitro binding affinity towards serotonin 5-HT1A receptor by the displacement of [3H]-8-OH-DPAT from rat hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282964(CHEMBL300556 | N-{1-(4-Fluoro-phenyl)-4-[4-(5-fluo...)
Affinity DataIC50: >49nMAssay Description:In vitro binding affinity of the compound towards sigma receptor by the displacement of [3H]-PPP from guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282967(1-Cyclohexyl-1-(4-fluoro-phenyl)-4-[4-(5-fluoro-py...)
Affinity DataIC50:  50nMAssay Description:In vitro binding affinity towards serotonin 5-HT1A receptor by the displacement of [3H]-8-OH-DPAT from rat hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282976(5-Fluoro-2-{4-[3-(4-fluoro-phenylsulfanyl)-propyl]...)
Affinity DataIC50:  51nMAssay Description:In vitro binding affinity of the compound towards sigma receptor by the displacement of [3H]-PPP from guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282958(1-Cyclohexyl-4-[4-(5-fluoro-pyrimidin-2-yl)-pipera...)
Affinity DataIC50:  52nMAssay Description:In vitro binding affinity of the compound towards sigma receptor by the displacement of [3H]-PPP from guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282963(5-Fluoro-2-{4-[4-(4-fluoro-phenyl)-butyl]-piperazi...)
Affinity DataIC50:  71nMAssay Description:In vitro binding affinity towards serotonin 5-HT1A receptor by the displacement of [3H]-8-OH-DPAT from rat hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282960(1-(4-Fluoro-naphthalen-1-yl)-4-[4-(5-fluoro-pyrimi...)
Affinity DataIC50:  88nMAssay Description:In vitro binding affinity of the compound towards sigma receptor by the displacement of [3H]-PPP from guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282961(5-Fluoro-2-{4-[3-(4-fluoro-phenoxy)-propyl]-pipera...)
Affinity DataIC50:  89nMAssay Description:In vitro binding affinity of the compound towards sigma receptor by the displacement of [3H]-PPP from guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282965(4-Fluoro-N-{1-(4-fluoro-phenyl)-4-[4-(5-fluoro-pyr...)
Affinity DataIC50: >100nMAssay Description:In vitro binding affinity of the compound towards sigma receptor by the displacement of [3H]-PPP from guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282965(4-Fluoro-N-{1-(4-fluoro-phenyl)-4-[4-(5-fluoro-pyr...)
Affinity DataIC50:  106nMAssay Description:In vitro binding affinity towards serotonin 5-HT1A receptor by the displacement of [3H]-8-OH-DPAT from rat hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50002238((R)1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-...)
Affinity DataIC50:  112nMAssay Description:In vitro binding affinity of the compound towards sigma receptor by the displacement of [3H]-PPP from guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282976(5-Fluoro-2-{4-[3-(4-fluoro-phenylsulfanyl)-propyl]...)
Affinity DataIC50:  129nMAssay Description:In vitro binding affinity towards serotonin 5-HT1A receptor by the displacement of [3H]-8-OH-DPAT from rat hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282961(5-Fluoro-2-{4-[3-(4-fluoro-phenoxy)-propyl]-pipera...)
Affinity DataIC50:  141nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor by the displacement of [3H]-spiperone from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282961(5-Fluoro-2-{4-[3-(4-fluoro-phenoxy)-propyl]-pipera...)
Affinity DataIC50:  145nMAssay Description:In vitro binding affinity towards serotonin 5-HT1A receptor by the displacement of [3H]-8-OH-DPAT from rat hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282963(5-Fluoro-2-{4-[4-(4-fluoro-phenyl)-butyl]-piperazi...)
Affinity DataIC50:  212nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor by the displacement of [3H]-spiperone from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282959(5-Fluoro-2-{4-[4-(4-fluoro-naphthalen-1-yl)-butyl]...)
Affinity DataIC50:  213nMAssay Description:In vitro binding affinity of the compound towards sigma receptor by the displacement of [3H]-PPP from guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282962(1-(4-Fluoro-naphthalen-1-yl)-4-[4-(5-fluoro-pyrimi...)
Affinity DataIC50:  215nMAssay Description:In vitro binding affinity of the compound towards sigma receptor by the displacement of [3H]-PPP from guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282970(2-(4-Fluoro-phenyl)-5-[4-(5-fluoro-pyrimidin-2-yl)...)
Affinity DataIC50:  227nMAssay Description:In vitro binding affinity of the compound towards sigma receptor by the displacement of [3H]-PPP from guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282958(1-Cyclohexyl-4-[4-(5-fluoro-pyrimidin-2-yl)-pipera...)
Affinity DataIC50:  257nMAssay Description:In vitro binding affinity towards serotonin 5-HT1A receptor by the displacement of [3H]-8-OH-DPAT from rat hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282964(CHEMBL300556 | N-{1-(4-Fluoro-phenyl)-4-[4-(5-fluo...)
Affinity DataIC50:  289nMAssay Description:In vitro binding affinity towards serotonin 5-HT1A receptor by the displacement of [3H]-8-OH-DPAT from rat hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282968(2-[4-(4-Cyclohexyl-butyl)-piperazin-1-yl]-5-fluoro...)
Affinity DataIC50:  315nMAssay Description:In vitro binding affinity towards serotonin 5-HT1A receptor by the displacement of [3H]-8-OH-DPAT from rat hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50002238((R)1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-...)
Affinity DataIC50:  320nMAssay Description:In vitro binding affinity towards serotonin 5-HT1A receptor by the displacement of [3H]-8-OH-DPAT from rat hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282967(1-Cyclohexyl-1-(4-fluoro-phenyl)-4-[4-(5-fluoro-py...)
Affinity DataIC50:  336nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor by the displacement of [3H]-spiperone from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282962(1-(4-Fluoro-naphthalen-1-yl)-4-[4-(5-fluoro-pyrimi...)
Affinity DataIC50:  345nMAssay Description:In vitro binding affinity towards serotonin 5-HT1A receptor by the displacement of [3H]-8-OH-DPAT from rat hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282959(5-Fluoro-2-{4-[4-(4-fluoro-naphthalen-1-yl)-butyl]...)
Affinity DataIC50:  414nMAssay Description:In vitro binding affinity towards serotonin 5-HT1A receptor by the displacement of [3H]-8-OH-DPAT from rat hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282972(5-Fluoro-2-{4-[3-(4-fluoro-benzenesulfonyl)-propyl...)
Affinity DataIC50:  461nMAssay Description:In vitro binding affinity towards serotonin 5-HT1A receptor by the displacement of [3H]-8-OH-DPAT from rat hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282965(4-Fluoro-N-{1-(4-fluoro-phenyl)-4-[4-(5-fluoro-pyr...)
Affinity DataIC50:  468nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor by the displacement of [3H]-spiperone from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282966(CHEMBL58282 | N-{1-Cyclohexyl-4-[4-(5-fluoro-pyrim...)
Affinity DataIC50:  504nMAssay Description:In vitro binding affinity of the compound towards sigma receptor by the displacement of [3H]-PPP from guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282970(2-(4-Fluoro-phenyl)-5-[4-(5-fluoro-pyrimidin-2-yl)...)
Affinity DataIC50:  504nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor by the displacement of [3H]-spiperone from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282960(1-(4-Fluoro-naphthalen-1-yl)-4-[4-(5-fluoro-pyrimi...)
Affinity DataIC50:  562nMAssay Description:In vitro binding affinity towards serotonin 5-HT1A receptor by the displacement of [3H]-8-OH-DPAT from rat hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282975(Benzoic acid 1-(4-fluoro-phenyl)-4-[4-(5-fluoro-py...)
Affinity DataIC50:  581nMAssay Description:In vitro binding affinity towards serotonin 5-HT1A receptor by the displacement of [3H]-8-OH-DPAT from rat hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282959(5-Fluoro-2-{4-[4-(4-fluoro-naphthalen-1-yl)-butyl]...)
Affinity DataIC50:  590nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor by the displacement of [3H]-spiperone from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282966(CHEMBL58282 | N-{1-Cyclohexyl-4-[4-(5-fluoro-pyrim...)
Affinity DataIC50:  760nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor by the displacement of [3H]-spiperone from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282974(CHEMBL58283 | N-{1-Cyclohexyl-4-[4-(5-fluoro-pyrim...)
Affinity DataIC50:  760nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor by the displacement of [3H]-spiperone from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282960(1-(4-Fluoro-naphthalen-1-yl)-4-[4-(5-fluoro-pyrimi...)
Affinity DataIC50:  1.01E+3nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor by the displacement of [3H]-spiperone from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282971(4-Fluoro-N-{1-(4-fluoro-phenyl)-4-[4-(5-fluoro-pyr...)
Affinity DataIC50:  1.52E+3nMAssay Description:In vitro binding affinity of the compound towards sigma receptor by the displacement of [3H]-PPP from guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50002238((R)1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-...)
Affinity DataIC50:  1.70E+3nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor by the displacement of [3H]-spiperone from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282971(4-Fluoro-N-{1-(4-fluoro-phenyl)-4-[4-(5-fluoro-pyr...)
Affinity DataIC50:  1.81E+3nMAssay Description:In vitro binding affinity towards serotonin 5-HT1A receptor by the displacement of [3H]-8-OH-DPAT from rat hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282971(4-Fluoro-N-{1-(4-fluoro-phenyl)-4-[4-(5-fluoro-pyr...)
Affinity DataIC50:  3.40E+3nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor by the displacement of [3H]-spiperone from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282975(Benzoic acid 1-(4-fluoro-phenyl)-4-[4-(5-fluoro-py...)
Affinity DataIC50:  3.50E+3nMAssay Description:In vitro binding affinity of the compound towards sigma receptor by the displacement of [3H]-PPP from guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails Article