Reaction Details  Report a problem with these data
Cell Reactant:
Phospholipase C-γ1 SH2 domain (PLCC)
Syringe Reactant:
BDBM225239
Meas. Tech.:
Enzyme Inhibition
Entry Date.:
05/11/17
ΔG°:
-57.5±n/a (kJ/mole)
pH:
7.4±0
Temperature:
298.15±0 (K)
ΔH° :
-9.71±0.3 (kJ/mole)
ΔS° :
0.104±0.0205 (kJ/mole-K)
Citation
 McKercher, MA; Guan, X; Tan, Z; Wuttke, DS Multimodal Recognition of Diverse Peptides by the C-Terminal SH2 Domain of Phospholipase C-¿1 Protein. Biochemistry 56:2225-2237 (2017) [PubMed]  Article
Cell React
Name:
Phospholipase C-γ1 SH2 domain (PLCC)
Synonyms:
PLC1 | PLCG1 | PLCG1_HUMAN
Type:
Protein
Mol. Mass.:
11560.59
Organism:
Homo sapiens (Human)
Description:
Human phospholipase C-γ1 C-terminal SH2 domain (663-759 aa)
Residue:
97
Sequence:
HESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEE
  
Syringe React
Name:
BDBM225239
Synonyms:
PDGFRB-pep
Type:
Small organic molecule
Emp. Form.:
C56H85N12O23P
Mol. Mass.:
1325.3145
SMILES:
CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](C)N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(O)=O)C(O)=O |r|
Structure:
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