Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 1A
Ligand
BDBM31076
Substrate
Not Available
Meas. Tech.
Dose Response Assay for Agonists of 5-Hydroxytryptamine (Serotonin) Receptor Subtype 1A (5HT1A)
pH
7.4±n/a
Temperature
296.15±n/a K
IC50
2602±n/a nM
Citation
 PubChem, PC Dose Response Cell Based Assay for Antagonists of the 5-Hydroxytryptamine Receptor Subtype 1A (5HT1A) PubChem Bioassay (2007)[AID] 
Target
Name:
5-hydroxytryptamine receptor 1A
Synonyms:
5-HT-1A | 5-HT1A | 5-hydroxytryptamine receptor 1A (5-HT-1A) | 5HT1A_HUMAN | ADRB2RL1 | ADRBRL1 | Dopamine D2 receptor and serotonin 1a receptor | G-21 | HTR1A | Serotonin receptor 1A
Type:
n/a
Mol. Mass.:
46122.49
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
422
Sequence:
MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ
  
Inhibitor
Name:
BDBM31076
Synonyms:
2-[1-(4-methoxyphenyl)tetrazol-5-yl]sulfonyl-1-piperidin-1-ylethanone | 2-[1-(4-methoxyphenyl)tetrazol-5-yl]sulfonyl-1-piperidino-ethanone | 2-[[1-(4-methoxyphenyl)-1,2,3,4-tetrazol-5-yl]sulfonyl]-1-piperidin-1-yl-ethanone | 2-[[1-(4-methoxyphenyl)-5-tetrazolyl]sulfonyl]-1-(1-piperidinyl)ethanone | MLS000119145 | SMR000096080 | cid_1263400
Type:
Small organic molecule
Emp. Form.:
C15H19N5O4S
Mol. Mass.:
365.407
SMILES:
COc1ccc(cc1)-n1nnnc1S(=O)(=O)CC(=O)N1CCCCC1
Structure:
Search PDB for entries with ligand similarity:
Substrate
Name:
Not Available
Synonyms:
n/a
Type:
n/a
Mol. Mass.:
358.43
Organism:
n/a
Description:
n/a
Residue:
3
Sequence:
NA