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Target
Bcl-2-related protein A1
Ligand
BDBM34170
Substrate
FITC-Ahx-EDIIRNIARHLAQVGDSMDR
Meas. Tech.
HTS discovery of chemical inhibitors of anti-apoptotic protein Bfl-1
pH
7±n/a
Temperature
296.15±n/a K
IC50
14459±0 nM
Citation
 PubChem, PC HTS discovery of chemical inhibitors of anti-apoptotic protein Bfl-1 PubChem Bioassay (2008)[AID] 
Target
Name:
Bcl-2-related protein A1
Synonyms:
A1 | A1-A | B-cell leukemia/lymphoma 2 related protein A1a | B2LA1_MOUSE | Bcl2a1 | Bcl2a1a | Bfl-1 | Bfl1 | Hemopoietic-specific early response protein | Protein BFL-1
Type:
Apoptosis regulator protein
Mol. Mass.:
19909.74
Organism:
Mus musculus (Mouse)
Description:
gi_11024684
Residue:
172
Sequence:
MAESELMHIHSLAEHYLQYVLQVPAFESAPSQACRVLQRVAFSVQKEVEKNLKSYLDDFHVESIDTARIIFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLPQEQIALDVCAYKQVSSFVAEFIMNNTGEWIRQNGGWEDGFIKKFEPKSGWLTFLQMTGQIWEMLFLLK
  
Inhibitor
Name:
BDBM34170
Synonyms:
2-[(2-ethyl-1-keto-7,8-dihydro-6H-cyclopenta[2,3]thieno[2,4-b]pyrimidin-3-yl)thio]acetic acid | 2-[(2-ethyl-1-oxidanylidene-7,8-dihydro-6H-cyclopenta[2,3]thieno[2,4-b]pyrimidin-3-yl)sulfanyl]ethanoic acid | 2-[(2-ethyl-1-oxo-7,8-dihydro-6H-cyclopenta[2,3]thieno[2,4-b]pyrimidin-3-yl)sulfanyl]acetic acid | 2-[(2-ethyl-1-oxo-7,8-dihydro-6H-cyclopenta[2,3]thieno[2,4-b]pyrimidin-3-yl)thio]acetic acid | MLS000069140 | SMR000039043 | cid_658077
Type:
Small organic molecule
Emp. Form.:
C13H14N2O3S2
Mol. Mass.:
310.392
SMILES:
CCn1c(SCC(O)=O)nc2sc3CCCc3c2c1=O
Structure:
Search PDB for entries with ligand similarity:
Substrate
Name:
FITC-Ahx-EDIIRNIARHLAQVGDSMDR
Synonyms:
FITC-Bid peptide
Type:
fluorescein-labeled peptide
Mol. Mass.:
358.43
Organism:
n/a
Description:
n/a
Residue:
3
Sequence:
NA