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Target
Sphingosine 1-phosphate receptor 1
Ligand
BDBM36891
Substrate
n/a
Meas. Tech.
Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Parental Cell Line Counter Screen 60K MLSMR
EC50
>95100±n/a nM
Citation
 PubChem, PC Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Parental Cell Line Counter Screen 60K MLSMR PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 1
Synonyms:
CHEDG1 | EDG1 | Endothelial differentiation G-protein coupled receptor 1 | S1P receptor | S1P1 | S1PR1 | S1PR1_HUMAN | Sphingosine 1-phosphate receptor 1 (S1PR1) | Sphingosine 1-phosphate receptor Edg-1
Type:
Enzyme
Mol. Mass.:
42836.02
Organism:
Homo sapiens (Human)
Description:
P21453
Residue:
382
Sequence:
MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSHPQKDEGDNPETIMSSGNVNSSS
  
Inhibitor
Name:
BDBM36891
Synonyms:
1-[1-(4-methoxyphenyl)-2-methyl-5-oxidanyl-indol-3-yl]ethanone | 1-[5-hydroxy-1-(4-methoxyphenyl)-2-methyl-3-indolyl]ethanone | 1-[5-hydroxy-1-(4-methoxyphenyl)-2-methyl-indol-3-yl]ethanone | 1-[5-hydroxy-1-(4-methoxyphenyl)-2-methylindol-3-yl]ethanone | MLS000027600 | SMR000034636 | cid_658914
Type:
Small organic molecule
Emp. Form.:
C18H17NO3
Mol. Mass.:
295.3325
SMILES:
COc1ccc(cc1)-n1c(C)c(C(C)=O)c2cc(O)ccc12
Structure:
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