Reaction Details Report a problem with these data
Target
Sphingosine 1-phosphate receptor 3
Ligand
BDBM37419
Substrate
n/a
Meas. Tech.
Dose Response Assay for S1P3 Antagonists
IC50
>5530±n/a nM
Citation
 PubChem, PC Dose Response Assay for S1P3 Antagonists PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 3
Synonyms:
C9orf108 | C9orf47 | EDG3 | Endothelial differentiation G-protein coupled receptor 3 | S1P receptor 3 | S1P receptor Edg-3 | S1P3 | S1PR3 | S1PR3_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor 3 (S1P3) | Sphingosine 1-phosphate receptor Edg-3
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42278.13
Organism:
Homo sapiens (Human)
Description:
Q99500
Residue:
378
Sequence:
MATALPPRLQPVRGNETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMALLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNCLVRGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAPSSCIMDKNAALQNGIFCN
  
Inhibitor
Name:
BDBM37419
Synonyms:
MLS000065442 | N-(2-furanylmethyl)-3-[[(4-methylphenyl)-oxomethyl]amino]benzamide | N-(2-furfuryl)-3-(p-toluoylamino)benzamide | N-(2-furylmethyl)-3-[(4-methylbenzoyl)amino]benzamide | N-(furan-2-ylmethyl)-3-[(4-methylbenzoyl)amino]benzamide | N-(furan-2-ylmethyl)-3-[(4-methylphenyl)carbonylamino]benzamide | SMR000079286 | cid_2221556
Type:
Small organic molecule
Emp. Form.:
C20H18N2O3
Mol. Mass.:
334.3685
SMILES:
Cc1ccc(cc1)C(=O)Nc1cccc(c1)C(=O)NCc1ccco1
Structure:
Search PDB for entries with ligand similarity: