Reaction Details Report a problem with these data
Target
N-formyl peptide receptor 2
Ligand
BDBM37818
Substrate
n/a
Meas. Tech.
Dose Response Assay for Formylpeptide Receptor-Like-1 (FPRL1) Ligands and Dose Response Counter-Screen Assay for Formylpeptide Receptor (FPR) Ligands
Ki
>40300±n/a nM
Comments
Extracted from aid = 520 and tid = 2
Citation
 PubChem, PC Dose Response Assay for Formylpeptide Receptor-Like-1 (FPRL1) Ligands and Dose Response Counter-Screen Assay for Formylpeptide Receptor (FPR) Ligands PubChem Bioassay (2007)[AID] 
Target
Name:
N-formyl peptide receptor 2
Synonyms:
ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38968.35
Organism:
Homo sapiens (Human)
Description:
P25090
Residue:
351
Sequence:
METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
  
Inhibitor
Name:
BDBM37818
Synonyms:
1-(5-methyl-1,3,4-thiadiazol-2-yl)-4-oxidanyl-2-(4-prop-2-enoxyphenyl)-3-thiophen-2-ylcarbonyl-2H-pyrrol-5-one | 4-hydroxy-1-(5-methyl-1,3,4-thiadiazol-2-yl)-2-(4-prop-2-enoxyphenyl)-3-(thiophene-2-carbonyl)-2H-pyrrol-5-one | 4-hydroxy-1-(5-methyl-1,3,4-thiadiazol-2-yl)-3-[oxo(thiophen-2-yl)methyl]-2-(4-prop-2-enoxyphenyl)-2H-pyrrol-5-one | 5-(4-Allyloxy-phenyl)-3-hydroxy-1-(5-methyl-[1,3,4]thiadiazol-2-yl)-4-(thiophene-2-carbonyl)-1,5-dihydro-pyrrol-2-one | 5-(4-allyloxyphenyl)-3-hydroxy-1-(5-methyl-1,3,4-thiadiazol-2-yl)-4-(2-thenoyl)-3-pyrrolin-2-one | MLS000121539 | SMR000118997 | cid_2911882
Type:
Small organic molecule
Emp. Form.:
C21H17N3O4S2
Mol. Mass.:
439.507
SMILES:
Cc1nnc(s1)N1C(C(C(=O)c2cccs2)C(=O)C1=O)c1ccc(OCC=C)cc1
Structure:
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