Reaction Details Report a problem with these data
Target
Dual specificity protein phosphatase 6
Ligand
BDBM34390
Substrate
n/a
Meas. Tech.
In vitro MKP-3 Phosphatase Dose Response Hit/Probe Assessment Assay
IC50
>50000±n/a nM
Citation
 PubChem, PC In vitro MKP-3 Phosphatase Dose Response Hit/Probe Assessment Assay PubChem Bioassay (2007)[AID] 
Target
Name:
Dual specificity protein phosphatase 6
Synonyms:
DUS6_RAT | Dusp6 | MAP kinase phosphatase 3 | MKP-3 | Mitogen-activated protein kinase phosphatase 3 | Mkp3
Type:
Enzyme
Mol. Mass.:
42303.19
Organism:
Rattus norvegicus
Description:
gi_16758752
Residue:
381
Sequence:
MIDTLRPVPFASEMAISKTVAWLNEQLELGNEQLLLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGNLPVRALFTRCEDRDRFTRRCGTDTVVLYDENSSDWNENTGGESVLGLLLKKLKDEGCRAFYLEGGFSKFQAEFALHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDIESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQQLYFTAPSNQNVYQVDSLQST
  
Inhibitor
Name:
BDBM34390
Synonyms:
MLS000043492 | N-(4-methoxyphenyl)-N-(4-methyl-2-sulfanylidene-1,3,2-dioxaphosphorinan-2-yl)carbamic acid methyl ester | N-(4-methoxyphenyl)-N-(4-methyl-2-thioxo-1,3,2-dioxaphosphorinan-2-yl)carbamic acid methyl ester | SMR000020309 | cid_3242273 | methyl 4-methoxyphenyl(4-methyl-2-sulfido-1,3,2-dioxaphosphinan-2-yl)carbamate | methyl N-(4-methoxyphenyl)-N-(4-methyl-2-sulfanylidene-1,3,2-dioxaphosphinan-2-yl)carbamate
Type:
Small organic molecule
Emp. Form.:
C13H18NO5PS
Mol. Mass.:
331.324
SMILES:
COC(=O)N(c1ccc(OC)cc1)P1(=S)OCCC(C)O1
Structure:
Search PDB for entries with ligand similarity: