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Target
Dual specificity protein phosphatase 1
Ligand
BDBM35403
Substrate
n/a
Meas. Tech.
In vitro MKP-1 Phosphatase Dose Response Active/Probe Assessment Assay - Reproducibility testing
IC50
46241±n/a nM
Citation
 PubChem, PC In vitro MKP-1 Phosphatase Dose Response Active/Probe Assessment Assay - Reproducibility testing PubChem Bioassay (2006)[AID] 
Target
Name:
Dual specificity protein phosphatase 1
Synonyms:
CL100 | DUS1_HUMAN | DUSP1 | Dual specificity protein phosphatase hVH1 | MAP kinase phosphatase 1 | MKP-1 | MKP1 | PTPN10 | Protein-tyrosine phosphatase CL100 | VH1
Type:
Protein phosphatase
Mol. Mass.:
39301.48
Organism:
Homo sapiens (Human)
Description:
gi_4758204
Residue:
367
Sequence:
MVMEVGTLDAGGLRALLGERAAQCLLLDCRSFFAFNAGHIAGSVNVRFSTIVRRRAKGAMGLEHIVPNAELRGRLLAGAYHAVVLLDERSAALDGAKRDGTLALAAGALCREARAAQVFFLKGGYEAFSASCPELCSKQSTPMGLSLPLSTSVPDSAESGCSSCSTPLYDQGGPVEILPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSWFNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAPHCSAEAGSPAMAVLDRGTSTTTVFNFPVSIPVHSTNSALSYLQSPITTSPSC
  
Inhibitor
Name:
BDBM35403
Synonyms:
MLS000094302 | SMR000029892 | cid_3242856 | methyl 2-{[(3-chloro-6-oxo-6a,7,8,9-tetrahydropyrido[3,2-e]pyrrolo[1,2-a]pyrazin-5(6H)-yl)acetyl]amino}benzoate
Type:
Small organic molecule
Emp. Form.:
C20H19ClN4O4
Mol. Mass.:
414.842
SMILES:
COC(=O)c1ccccc1NC(=O)CN1C(=O)C2CCCN2c2ncc(Cl)cc12
Structure:
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