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Target
Dual specificity protein phosphatase 6
Ligand
BDBM22851
Substrate
n/a
Meas. Tech.
In vitro MKP-3 Phosphatase Dose Response Active/Probe Assessment Assay - Reproducibility testing
IC50
>50000±n/a nM
Citation
 PubChem, PC In vitro MKP-3 Phosphatase Dose Response Active/Probe Assessment Assay - Reproducibility testing PubChem Bioassay (2007)[AID] 
Target
Name:
Dual specificity protein phosphatase 6
Synonyms:
DUS6_RAT | Dusp6 | MAP kinase phosphatase 3 | MKP-3 | Mitogen-activated protein kinase phosphatase 3 | Mkp3
Type:
Enzyme
Mol. Mass.:
42303.19
Organism:
Rattus norvegicus
Description:
gi_16758752
Residue:
381
Sequence:
MIDTLRPVPFASEMAISKTVAWLNEQLELGNEQLLLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGNLPVRALFTRCEDRDRFTRRCGTDTVVLYDENSSDWNENTGGESVLGLLLKKLKDEGCRAFYLEGGFSKFQAEFALHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDIESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQQLYFTAPSNQNVYQVDSLQST
  
Inhibitor
Name:
BDBM22851
Synonyms:
1,2-Dione-Based Compound, 8 | 1,2-dihydronaphthalene-1,2-dione | 1,2-naphthoquinone | CHEMBL52347 | cid_10667
Type:
Small organic molecule
Emp. Form.:
C10H6O2
Mol. Mass.:
158.1534
SMILES:
O=C1C=Cc2ccccc2C1=O |c:2|
Structure:
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