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Target
Bcl-2-related protein A1
Ligand
BDBM39129
Substrate
n/a
Meas. Tech.
TR-FRET secondary assay for HTS discovery of chemical inhibitors of anti-apoptotic protein Bfl-1
IC50
5830±760 nM
Citation
 PubChem, PC TR-FRET secondary assay for HTS discovery of chemical inhibitors of anti-apoptotic protein Bfl-1 PubChem Bioassay (2008)[AID] 
Target
Name:
Bcl-2-related protein A1
Synonyms:
A1 | A1-A | B-cell leukemia/lymphoma 2 related protein A1a | B2LA1_MOUSE | Bcl2a1 | Bcl2a1a | Bfl-1 | Bfl1 | Hemopoietic-specific early response protein | Protein BFL-1
Type:
Apoptosis regulator protein
Mol. Mass.:
19909.74
Organism:
Mus musculus (Mouse)
Description:
gi_11024684
Residue:
172
Sequence:
MAESELMHIHSLAEHYLQYVLQVPAFESAPSQACRVLQRVAFSVQKEVEKNLKSYLDDFHVESIDTARIIFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLPQEQIALDVCAYKQVSSFVAEFIMNNTGEWIRQNGGWEDGFIKKFEPKSGWLTFLQMTGQIWEMLFLLK
  
Inhibitor
Name:
BDBM39129
Synonyms:
3-chloranyl-1-(2-chlorophenyl)-4-morpholin-4-yl-pyrrole-2,5-dione | 3-chloro-1-(2-chlorophenyl)-4-(4-morpholinyl)pyrrole-2,5-dione | 3-chloro-1-(2-chlorophenyl)-4-morpholin-4-ylpyrrole-2,5-dione | 3-chloro-1-(2-chlorophenyl)-4-morpholino-3-pyrroline-2,5-quinone | MLS-0013275.0001 | cid_796318
Type:
Small organic molecule
Emp. Form.:
C14H12Cl2N2O3
Mol. Mass.:
327.163
SMILES:
ClC1=C(N2CCOCC2)C(=O)N(C1=O)c1ccccc1Cl |c:1|
Structure:
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