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Target
Bcl-2-related protein A1
Ligand
BDBM39135
Substrate
n/a
Meas. Tech.
TR-FRET secondary assay for HTS discovery of chemical inhibitors of anti-apoptotic protein Bfl-1
IC50
20100±1050 nM
Citation
 PubChem, PC TR-FRET secondary assay for HTS discovery of chemical inhibitors of anti-apoptotic protein Bfl-1 PubChem Bioassay (2008)[AID] 
Target
Name:
Bcl-2-related protein A1
Synonyms:
A1 | A1-A | B-cell leukemia/lymphoma 2 related protein A1a | B2LA1_MOUSE | Bcl2a1 | Bcl2a1a | Bfl-1 | Bfl1 | Hemopoietic-specific early response protein | Protein BFL-1
Type:
Apoptosis regulator protein
Mol. Mass.:
19909.74
Organism:
Mus musculus (Mouse)
Description:
gi_11024684
Residue:
172
Sequence:
MAESELMHIHSLAEHYLQYVLQVPAFESAPSQACRVLQRVAFSVQKEVEKNLKSYLDDFHVESIDTARIIFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLPQEQIALDVCAYKQVSSFVAEFIMNNTGEWIRQNGGWEDGFIKKFEPKSGWLTFLQMTGQIWEMLFLLK
  
Inhibitor
Name:
BDBM39135
Synonyms:
1-[2,6-bis(chloranyl)-3-methyl-phenyl]-3,4-bis(chloranyl)pyrrole-2,5-dione | 3,4-dichloro-1-(2,6-dichloro-3-methyl-phenyl)-3-pyrroline-2,5-quinone | 3,4-dichloro-1-(2,6-dichloro-3-methylphenyl)pyrrole-2,5-dione | MLS-0090825.0001 | cid_16654636
Type:
Small organic molecule
Emp. Form.:
C11H5Cl4NO2
Mol. Mass.:
324.975
SMILES:
Cc1ccc(Cl)c(N2C(=O)C(Cl)=C(Cl)C2=O)c1Cl |t:11|
Structure:
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