Reaction Details Report a problem with these data
Target
N-formyl peptide receptor 2
Ligand
BDBM40422
Substrate
n/a
Meas. Tech.
Formylpeptide Receptor (FPR) Ligand Structure Activity Relationship (SAR) Analysis : Dose Response Assay Counterscreen Against Formyl Peptide Receptor-Like-1 (FPRL1)
Ki
>40300±n/a nM
Citation
 PubChem, PC Formylpeptide Receptor (FPR) Ligand Structure Activity Relationship (SAR) Analysis : Dose Response Assay Counterscreen Against Formyl Peptide Receptor-Like-1 (FPRL1)  PubChem Bioassay (2007)[AID] 
Target
Name:
N-formyl peptide receptor 2
Synonyms:
ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38968.35
Organism:
Homo sapiens (Human)
Description:
P25090
Residue:
351
Sequence:
METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
  
Inhibitor
Name:
BDBM40422
Synonyms:
2-(3,4-dimethoxyphenyl)-3-(furan-2-carbonyl)-4-hydroxy-1-(3-morpholin-4-ylpropyl)-2H-pyrrol-5-one | 2-(3,4-dimethoxyphenyl)-3-(furan-2-ylcarbonyl)-1-(3-morpholin-4-ylpropyl)-4-oxidanyl-2H-pyrrol-5-one | 2-(3,4-dimethoxyphenyl)-3-[2-furanyl(oxo)methyl]-4-hydroxy-1-[3-(4-morpholinyl)propyl]-2H-pyrrol-5-one | 5-(3,4-dimethoxyphenyl)-4-(2-furoyl)-3-hydroxy-1-(3-morpholinopropyl)-3-pyrrolin-2-one | UNM000003553701 | cid_2908584
Type:
Small organic molecule
Emp. Form.:
C24H28N2O7
Mol. Mass.:
456.4883
SMILES:
COc1ccc(cc1OC)C1C(C(=O)c2ccco2)C(=O)C(=O)N1CCCN1CCOCC1
Structure:
Search PDB for entries with ligand similarity: