Reaction Details Report a problem with these data
Target
N-formyl peptide receptor 2
Ligand
BDBM40450
Substrate
n/a
Meas. Tech.
Formylpeptide Receptor (FPR) Ligand Structure Activity Relationship (SAR) Analysis : Dose Response Assay Counterscreen Against Formyl Peptide Receptor-Like-1 (FPRL1)
Ki
>40300±n/a nM
Citation
 PubChem, PC Formylpeptide Receptor (FPR) Ligand Structure Activity Relationship (SAR) Analysis : Dose Response Assay Counterscreen Against Formyl Peptide Receptor-Like-1 (FPRL1)  PubChem Bioassay (2007)[AID] 
Target
Name:
N-formyl peptide receptor 2
Synonyms:
ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38968.35
Organism:
Homo sapiens (Human)
Description:
P25090
Residue:
351
Sequence:
METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
  
Inhibitor
Name:
BDBM40450
Synonyms:
N-(2,6-dimethylphenyl)-2-[(1-oxo-2-thiophen-2-ylethyl)amino]-2-phenylacetamide | N-(2,6-dimethylphenyl)-2-phenyl-2-(2-thiophen-2-ylethanoylamino)ethanamide | N-(2,6-dimethylphenyl)-2-phenyl-2-[(2-thiophen-2-ylacetyl)amino]acetamide | N-(2,6-dimethylphenyl)-2-phenyl-2-[[2-(2-thienyl)acetyl]amino]acetamide | UNM000003608101 | cid_4656066
Type:
Small organic molecule
Emp. Form.:
C22H22N2O2S
Mol. Mass.:
378.487
SMILES:
Cc1cccc(C)c1NC(=O)C(NC(=O)Cc1cccs1)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: