Reaction Details Report a problem with these data
Target
N-formyl peptide receptor 2
Ligand
BDBM40402
Substrate
n/a
Meas. Tech.
Formylpeptide Receptor (FPR) Ligand Structure Activity Relationship (SAR) Analysis : Dose Response Assay Counterscreen Against Formyl Peptide Receptor-Like-1 (FPRL1)
IC50
>66700±n/a nM
Citation
 PubChem, PC Formylpeptide Receptor (FPR) Ligand Structure Activity Relationship (SAR) Analysis : Dose Response Assay Counterscreen Against Formyl Peptide Receptor-Like-1 (FPRL1)  PubChem Bioassay (2007)[AID] 
Target
Name:
N-formyl peptide receptor 2
Synonyms:
ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38968.35
Organism:
Homo sapiens (Human)
Description:
P25090
Residue:
351
Sequence:
METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
  
Inhibitor
Name:
BDBM40402
Synonyms:
2-furancarboxylic acid [3-(2-methoxyphenyl)-4-oxo-2-(trifluoromethyl)-1-benzopyran-7-yl] ester | UNM000003530201 | [3-(2-methoxyphenyl)-4-oxidanylidene-2-(trifluoromethyl)chromen-7-yl] furan-2-carboxylate | [3-(2-methoxyphenyl)-4-oxo-2-(trifluoromethyl)chromen-7-yl] furan-2-carboxylate | cid_1185399 | furan-2-carboxylic acid [4-keto-3-(2-methoxyphenyl)-2-(trifluoromethyl)chromen-7-yl] ester
Type:
Small organic molecule
Emp. Form.:
C22H13F3O6
Mol. Mass.:
430.3302
SMILES:
COc1ccccc1-c1c(oc2cc(OC(=O)c3ccco3)ccc2c1=O)C(F)(F)F |(7.08,-4.42,;7.08,-2.88,;5.75,-2.11,;4.41,-2.88,;3.08,-2.11,;3.08,-.57,;4.41,.2,;5.75,-.57,;7.08,.2,;7.08,1.74,;8.41,2.51,;9.75,1.74,;11.13,2.57,;12.52,1.77,;13.85,2.55,;15.19,1.78,;15.19,.24,;16.52,2.56,;16.67,4.09,;18.18,4.42,;18.95,3.09,;17.93,1.94,;12.52,.17,;11.13,-.62,;9.75,.2,;8.41,-.57,;8.41,-2.11,;5.75,2.51,;4.41,3.28,;6.52,3.85,;4.98,1.18,)|
Structure:
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