Reaction Details Report a problem with these data
Target
N-formyl peptide receptor 2
Ligand
BDBM40414
Substrate
n/a
Meas. Tech.
Formylpeptide Receptor (FPR) Ligand Structure Activity Relationship (SAR) Analysis : Dose Response Assay Counterscreen Against Formyl Peptide Receptor-Like-1 (FPRL1)
IC50
>66700±n/a nM
Citation
 PubChem, PC Formylpeptide Receptor (FPR) Ligand Structure Activity Relationship (SAR) Analysis : Dose Response Assay Counterscreen Against Formyl Peptide Receptor-Like-1 (FPRL1)  PubChem Bioassay (2007)[AID] 
Target
Name:
N-formyl peptide receptor 2
Synonyms:
ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38968.35
Organism:
Homo sapiens (Human)
Description:
P25090
Residue:
351
Sequence:
METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
  
Inhibitor
Name:
BDBM40414
Synonyms:
3-(3,4-dimethoxyphenyl)-7-hydroxy-8-(4-morpholinylmethyl)-2-(trifluoromethyl)-1-benzopyran-4-one | 3-(3,4-dimethoxyphenyl)-7-hydroxy-8-(morpholin-4-ylmethyl)-2-(trifluoromethyl)chromen-4-one | 3-(3,4-dimethoxyphenyl)-7-hydroxy-8-(morpholinomethyl)-2-(trifluoromethyl)chromone | 3-(3,4-dimethoxyphenyl)-8-(morpholin-4-ylmethyl)-7-oxidanyl-2-(trifluoromethyl)chromen-4-one | UNM000003540001 | cid_5449443
Type:
Small organic molecule
Emp. Form.:
C23H22F3NO6
Mol. Mass.:
465.4191
SMILES:
COc1ccc(cc1OC)-c1c(oc2c(CN3CCOCC3)c(O)ccc2c1=O)C(F)(F)F
Structure:
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