Reaction Details Report a problem with these data
Target
Sphingosine 1-phosphate receptor 3
Ligand
BDBM31002
Substrate
n/a
Meas. Tech.
S1P3 Dose Response Assay Counterscreen for 5-Hydroxytryptamine(Serotonin) Receptor Subtype 1E Agonists
EC50
>40000±n/a nM
Citation
 PubChem, PC S1P3 Dose Response Assay Counterscreen for 5-Hydroxytryptamine(Serotonin) Receptor Subtype 1E Agonists PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 3
Synonyms:
C9orf108 | C9orf47 | EDG3 | Endothelial differentiation G-protein coupled receptor 3 | S1P receptor 3 | S1P receptor Edg-3 | S1P3 | S1PR3 | S1PR3_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor 3 (S1P3) | Sphingosine 1-phosphate receptor Edg-3
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42278.13
Organism:
Homo sapiens (Human)
Description:
Q99500
Residue:
378
Sequence:
MATALPPRLQPVRGNETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMALLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNCLVRGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAPSSCIMDKNAALQNGIFCN
  
Inhibitor
Name:
BDBM31002
Synonyms:
2-(1-Methyl-5-phenyl-1H-imidazol-2-ylsulfanylmethyl)-3H-quinazolin-4-one | 2-[(1-methyl-5-phenyl-imidazol-2-yl)sulfanylmethyl]-1H-quinazolin-4-one | 2-[(1-methyl-5-phenylimidazol-2-yl)sulfanylmethyl]-1H-quinazolin-4-one | 2-[[(1-methyl-5-phenyl-2-imidazolyl)thio]methyl]-1H-quinazolin-4-one | 2-[[(1-methyl-5-phenyl-imidazol-2-yl)thio]methyl]-1H-quinazolin-4-one | MLS000077265 | SMR000002521 | cid_648716
Type:
Small organic molecule
Emp. Form.:
C19H16N4OS
Mol. Mass.:
348.422
SMILES:
Cn1c(SCc2nc3ccccc3c(=O)[nH]2)ncc1-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: