Reaction Details Report a problem with these data
Target
Estrogen receptor
Ligand
BDBM40479
Substrate
n/a
Meas. Tech.
Estrogen Receptor-alpha Coactivator Binding Potentiators Dose Response Confirmation
EC50
12500±n/a nM
Citation
 PubChem, PC Estrogen Receptor-alpha Coactivator Binding Potentiators Dose Response Confirmation PubChem Bioassay (2007)[AID] 
Target
Name:
Estrogen receptor
Synonyms:
ER | ER-alpha | ESR | ESR1 | ESR1_HUMAN | Estradiol receptor | Estrogen receptor | Estrogen receptor (ER alpha) | Estrogen receptor (ER-alpha) | Estrogen receptor alpha (ER alpha) | Estrogen receptor alpha (ER) | NR3A1 | Nuclear receptor subfamily 3 group A member 1
Type:
Protein
Mol. Mass.:
66230.44
Organism:
Homo sapiens (Human)
Description:
P03372
Residue:
595
Sequence:
MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV
  
Inhibitor
Name:
BDBM40479
Synonyms:
3-(2-Phenyl-imidazol-1-yl)-propionic acid | 3-(2-phenyl-1-imidazolyl)propanoic acid | 3-(2-phenylimidazol-1-yl)propanoic acid | 3-(2-phenylimidazol-1-yl)propionic acid | MLS000071948 | SMR000012026 | cid_644448
Type:
Small organic molecule
Emp. Form.:
C12H12N2O2
Mol. Mass.:
216.2359
SMILES:
OC(=O)CCn1ccnc1-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: