Reaction Details Report a problem with these data
Target
Estrogen receptor
Ligand
BDBM40483
Substrate
n/a
Meas. Tech.
Estrogen Receptor-alpha Coactivator Binding Potentiators Dose Response Confirmation
EC50
10933.33±n/a nM
Citation
 PubChem, PC Estrogen Receptor-alpha Coactivator Binding Potentiators Dose Response Confirmation PubChem Bioassay (2007)[AID] 
Target
Name:
Estrogen receptor
Synonyms:
ER | ER-alpha | ESR | ESR1 | ESR1_HUMAN | Estradiol receptor | Estrogen receptor | Estrogen receptor (ER alpha) | Estrogen receptor (ER-alpha) | Estrogen receptor alpha (ER alpha) | Estrogen receptor alpha (ER) | NR3A1 | Nuclear receptor subfamily 3 group A member 1
Type:
Protein
Mol. Mass.:
66230.44
Organism:
Homo sapiens (Human)
Description:
P03372
Residue:
595
Sequence:
MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV
  
Inhibitor
Name:
BDBM40483
Synonyms:
3-[6-(4-chlorophenyl)-2-methoxy-3-pyridinyl]-5-(2-furanyl)-1,2,4-oxadiazole | 3-[6-(4-chlorophenyl)-2-methoxy-3-pyridyl]-5-(2-furyl)-1,2,4-oxadiazole | 3-[6-(4-chlorophenyl)-2-methoxy-pyridin-3-yl]-5-(furan-2-yl)-1,2,4-oxadiazole | 3-[6-(4-chlorophenyl)-2-methoxypyridin-3-yl]-5-(furan-2-yl)-1,2,4-oxadiazole | 6-(4-Chloro-phenyl)-3-(5-furan-2-yl-[1,2,4]oxadiazol-3-yl)-2-methoxy-pyridine | MLS000076062 | SMR000014893 | cid_649431
Type:
Small organic molecule
Emp. Form.:
C18H12ClN3O3
Mol. Mass.:
353.759
SMILES:
COc1nc(ccc1-c1noc(n1)-c1ccco1)-c1ccc(Cl)cc1
Structure:
Search PDB for entries with ligand similarity: