Reaction Details Report a problem with these data
Target
Estrogen receptor
Ligand
BDBM40485
Substrate
n/a
Meas. Tech.
Estrogen Receptor-alpha Coactivator Binding Potentiators Dose Response Confirmation
EC50
23400.53±n/a nM
Citation
 PubChem, PC Estrogen Receptor-alpha Coactivator Binding Potentiators Dose Response Confirmation PubChem Bioassay (2007)[AID] 
Target
Name:
Estrogen receptor
Synonyms:
ER | ER-alpha | ESR | ESR1 | ESR1_HUMAN | Estradiol receptor | Estrogen receptor | Estrogen receptor (ER alpha) | Estrogen receptor (ER-alpha) | Estrogen receptor alpha (ER alpha) | Estrogen receptor alpha (ER) | NR3A1 | Nuclear receptor subfamily 3 group A member 1
Type:
Protein
Mol. Mass.:
66230.44
Organism:
Homo sapiens (Human)
Description:
P03372
Residue:
595
Sequence:
MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV
  
Inhibitor
Name:
BDBM40485
Synonyms:
(4-Benzyl-4H-thieno[3,2-b]pyrrol-5-yl)-(2,3-dihydro-indol-1-yl)-methanone | (4-benzylthieno[3,2-b]pyrrol-5-yl)-(2,3-dihydroindol-1-yl)methanone | (4-benzylthieno[3,2-b]pyrrol-5-yl)-indolin-1-yl-methanone | 2,3-dihydroindol-1-yl-[4-(phenylmethyl)-5-thieno[3,2-b]pyrrolyl]methanone | 2,3-dihydroindol-1-yl-[4-(phenylmethyl)thieno[3,2-b]pyrrol-5-yl]methanone | MLS000075101 | SMR000007351 | cid_651405
Type:
Small organic molecule
Emp. Form.:
C22H18N2OS
Mol. Mass.:
358.456
SMILES:
O=C(N1CCc2ccccc12)c1cc2sccc2n1Cc1ccccc1
Structure:
Search PDB for entries with ligand similarity: