Reaction Details Report a problem with these data
Target
Estrogen receptor
Ligand
BDBM40534
Substrate
n/a
Meas. Tech.
Estrogen Receptor-alpha Coactivator Binding Potentiators Dose Response Confirmation
EC50
12915.93±n/a nM
Citation
 PubChem, PC Estrogen Receptor-alpha Coactivator Binding Potentiators Dose Response Confirmation PubChem Bioassay (2007)[AID] 
Target
Name:
Estrogen receptor
Synonyms:
ER | ER-alpha | ESR | ESR1 | ESR1_HUMAN | Estradiol receptor | Estrogen receptor | Estrogen receptor (ER alpha) | Estrogen receptor (ER-alpha) | Estrogen receptor alpha (ER alpha) | Estrogen receptor alpha (ER) | NR3A1 | Nuclear receptor subfamily 3 group A member 1
Type:
Protein
Mol. Mass.:
66230.44
Organism:
Homo sapiens (Human)
Description:
P03372
Residue:
595
Sequence:
MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV
  
Inhibitor
Name:
BDBM40534
Synonyms:
1,5-dimethyl-4-oxidanylidene-N-(3,4,5-trimethoxyphenyl)pyrrolo[3,2-c]quinoline-2-carboxamide | 1,5-dimethyl-4-oxo-N-(3,4,5-trimethoxyphenyl)-2-pyrrolo[3,2-c]quinolinecarboxamide | 1,5-dimethyl-4-oxo-N-(3,4,5-trimethoxyphenyl)pyrrolo[3,2-c]quinoline-2-carboxamide | 4-keto-1,5-dimethyl-N-(3,4,5-trimethoxyphenyl)pyrrolo[3,2-c]quinoline-2-carboxamide | MLS000118077 | SMR000095025 | cid_5309406
Type:
Small organic molecule
Emp. Form.:
C23H23N3O5
Mol. Mass.:
421.4458
SMILES:
COc1cc(NC(=O)c2cc3c(n2C)c2ccccc2n(C)c3=O)cc(OC)c1OC
Structure:
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