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Target
Complement C1s subcomponent
Ligand
BDBM40872
Substrate
n/a
Meas. Tech.
Complement factor C1s IC50 from mixture screen
IC50
>50000±0 nM
Citation
 PubChem, PC Complement factor C1s IC50 from mixture screen PubChem Bioassay (2008)[AID] 
Target
Name:
Complement C1s subcomponent
Synonyms:
C1 esterase | C1S | C1S_HUMAN | Complement C1s | Complement C1s subcomponent | Complement C1s subcomponent heavy chain | Complement C1s subcomponent light chain | Complement component 1 subcomponent s | Trypsin | complement component 1, s subcomponent
Type:
Protein
Mol. Mass.:
76657.91
Organism:
Homo sapiens (Human)
Description:
P09871
Residue:
688
Sequence:
MWCIVLFSLLAWVYAEPTMYGEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQIISGDTEEGRLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAAYYVATDINECTDFVDVPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVFTALIGEIASPNYPKPYPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLVFVAGDRQFGPYCGHGFPGPLNIETKSNALDIIFQTDLTGQKKGWKLRYHGDPMPCPKEDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKLKCQPVDCGIPESIENGKVEDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNEVLGPELPKCVPVCGVPREPFEEKQRIIGGSDADIKNFPWQVFFDNPWAGGALINEYWVLTAAHVVEGNREPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKEVKVEKPTADAEAYVFTPNMICAGGEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCGTYGLYTRVKNYVDWIMKTMQENSTPRED
  
Inhibitor
Name:
BDBM40872
Synonyms:
1-(3,4,5-triethoxybenzoyl)isonipecotic acid ethyl ester | 1-[oxo-(3,4,5-triethoxyphenyl)methyl]-4-piperidinecarboxylic acid ethyl ester | MLS000061841 | SMR000070320 | cid_1147488 | ethyl 1-(3,4,5-triethoxybenzoyl)-4-piperidinecarboxylate | ethyl 1-(3,4,5-triethoxybenzoyl)piperidine-4-carboxylate | ethyl 1-(3,4,5-triethoxyphenyl)carbonylpiperidine-4-carboxylate
Type:
Small organic molecule
Emp. Form.:
C21H31NO6
Mol. Mass.:
393.4739
SMILES:
CCOC(=O)C1CCN(CC1)C(=O)c1cc(OCC)c(OCC)c(OCC)c1
Structure:
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