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Target
Procathepsin L
Ligand
BDBM41123
Substrate
n/a
Meas. Tech.
Cathepsin L dose-response confirmation
IC50
>50000±0 nM
Citation
 PubChem, PC Cathepsin L dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Procathepsin L
Synonyms:
CATL1_HUMAN | CTSL | CTSL CTSL1 | CTSL1 | Cathepsin L | Cathepsin L1 | Cathepsin L1 heavy chain | Cathepsin L1 light chain | MEP | Major excreted protein | cathepsin L preproprotein
Type:
Enzyme
Mol. Mass.:
37557.19
Organism:
Homo sapiens (Human)
Description:
Purchased from Calbiochem (San Diego, CA).
Residue:
333
Sequence:
MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
  
Inhibitor
Name:
BDBM41123
Synonyms:
MLS000075426 | N-methyl-N-(5-pyridin-3-yl-1,3,4-thiadiazol-2-yl)oxolane-3-carboxamide | N-methyl-N-[5-(3-pyridinyl)-1,3,4-thiadiazol-2-yl]-3-oxolanecarboxamide | N-methyl-N-[5-(3-pyridyl)-1,3,4-thiadiazol-2-yl]tetrahydrofuran-3-carboxamide | SMR000000612 | Tetrahydro-furan-3-carboxylic acid methyl-(5-pyridin-3-yl-[1,3,4]thiadiazol-2-yl)-amide | cid_645183
Type:
Small organic molecule
Emp. Form.:
C13H14N4O2S
Mol. Mass.:
290.341
SMILES:
CN(C(=O)C1CCOC1)c1nnc(s1)-c1cccnc1
Structure:
Search PDB for entries with ligand similarity: