Reaction Details Report a problem with these data
Target
Procathepsin L
Ligand
BDBM35499
Substrate
n/a
Meas. Tech.
Cathepsin L dose-response confirmation
IC50
1352.75±200.564 nM
Citation
 PubChem, PC Cathepsin L dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Procathepsin L
Synonyms:
CATL1_HUMAN | CTSL | CTSL CTSL1 | CTSL1 | Cathepsin L | Cathepsin L1 | Cathepsin L1 heavy chain | Cathepsin L1 light chain | MEP | Major excreted protein | cathepsin L preproprotein
Type:
Enzyme
Mol. Mass.:
37557.19
Organism:
Homo sapiens (Human)
Description:
Purchased from Calbiochem (San Diego, CA).
Residue:
333
Sequence:
MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
  
Inhibitor
Name:
BDBM35499
Synonyms:
(2-oxidanylidene-1,2-diphenyl-ethyl) 2-(furan-2-ylcarbonylamino)ethanoate | (2-oxo-1,2-diphenylethyl) 2-(furan-2-carbonylamino)acetate | 2-(2-furoylamino)acetic acid desyl ester | 2-[[2-furanyl(oxo)methyl]amino]acetic acid (2-oxo-1,2-diphenylethyl) ester | MLS000096499 | SMR000062349 | cid_2997975
Type:
Small organic molecule
Emp. Form.:
C21H17NO5
Mol. Mass.:
363.3634
SMILES:
O=C(CNC(=O)c1ccco1)OC(C(=O)c1ccccc1)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: