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Target
Procathepsin L
Ligand
BDBM41153
Substrate
n/a
Meas. Tech.
Cathepsin L dose-response confirmation
IC50
>50000±0 nM
Citation
 PubChem, PC Cathepsin L dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Procathepsin L
Synonyms:
CATL1_HUMAN | CTSL | CTSL CTSL1 | CTSL1 | Cathepsin L | Cathepsin L1 | Cathepsin L1 heavy chain | Cathepsin L1 light chain | MEP | Major excreted protein | cathepsin L preproprotein
Type:
Enzyme
Mol. Mass.:
37557.19
Organism:
Homo sapiens (Human)
Description:
Purchased from Calbiochem (San Diego, CA).
Residue:
333
Sequence:
MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
  
Inhibitor
Name:
BDBM41153
Synonyms:
3-(3,5-dimethyl-1-pyrazolyl)-N-(3-methylphenyl)propanamide | 3-(3,5-dimethyl-1H-pyrazol-1-yl)-N-(3-methylphenyl)propanamide | 3-(3,5-dimethylpyrazol-1-yl)-N-(3-methylphenyl)propanamide | 3-(3,5-dimethylpyrazol-1-yl)-N-(m-tolyl)propionamide | MLS000091274 | SMR000025836 | cid_3236386
Type:
Small organic molecule
Emp. Form.:
C15H19N3O
Mol. Mass.:
257.3309
SMILES:
Cc1cc(C)n(CCC(=O)Nc2cccc(C)c2)n1
Structure:
Search PDB for entries with ligand similarity: