Reaction Details Report a problem with these data
Target
Procathepsin L
Ligand
BDBM35515
Substrate
n/a
Meas. Tech.
Cathepsin L dose-response confirmation
IC50
5761.74±4092.76 nM
Citation
 PubChem, PC Cathepsin L dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Procathepsin L
Synonyms:
CATL1_HUMAN | CTSL | CTSL CTSL1 | CTSL1 | Cathepsin L | Cathepsin L1 | Cathepsin L1 heavy chain | Cathepsin L1 light chain | MEP | Major excreted protein | cathepsin L preproprotein
Type:
Enzyme
Mol. Mass.:
37557.19
Organism:
Homo sapiens (Human)
Description:
Purchased from Calbiochem (San Diego, CA).
Residue:
333
Sequence:
MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
  
Inhibitor
Name:
BDBM35515
Synonyms:
2-[[2-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-benzimidazolyl]-1-oxoethyl]amino]benzoic acid methyl ester | 2-[[2-[2-(4-aminofurazan-3-yl)benzimidazol-1-yl]acetyl]amino]benzoic acid methyl ester | MLS000050351 | SMR000077612 | cid_1505224 | methyl 2-({[2-(4-amino-1,2,5-oxadiazol-3-yl)-1H-benzimidazol-1-yl]acetyl}amino)benzoate | methyl 2-[2-[2-(4-azanyl-1,2,5-oxadiazol-3-yl)benzimidazol-1-yl]ethanoylamino]benzoate | methyl 2-[[2-[2-(4-amino-1,2,5-oxadiazol-3-yl)benzimidazol-1-yl]acetyl]amino]benzoate
Type:
Small organic molecule
Emp. Form.:
C19H16N6O4
Mol. Mass.:
392.3681
SMILES:
COC(=O)c1ccccc1NC(=O)Cn1c(nc2ccccc12)-c1nonc1N
Structure:
Search PDB for entries with ligand similarity: