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Target
Cathepsin S
Ligand
BDBM41325
Substrate
n/a
Meas. Tech.
Cathepsin S dose-response confirmation
IC50
>50000±0 nM
Citation
 PubChem, PC Cathepsin S dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Cathepsin S
Synonyms:
CATS_HUMAN | CTSS | Cathepsin S (Cat S) | cathepsin S preproprotein
Type:
Protein
Mol. Mass.:
37507.38
Organism:
Homo sapiens (Human)
Description:
P25774
Residue:
331
Sequence:
MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI
  
Inhibitor
Name:
BDBM41325
Synonyms:
MLS000047300 | N-[3-(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)-1-(2-furyl)-3-oxopropyl]-4-methoxybenzenesulfonamide | N-[3-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-1-(2-furanyl)-3-oxopropyl]-4-methoxybenzenesulfonamide | N-[3-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-1-(2-furyl)-3-keto-propyl]-4-methoxy-benzenesulfonamide | N-[3-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-1-(furan-2-yl)-3-oxidanylidene-propyl]-4-methoxy-benzenesulfonamide | N-[3-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-1-(furan-2-yl)-3-oxopropyl]-4-methoxybenzenesulfonamide | SMR000033311 | cid_3242514
Type:
Small organic molecule
Emp. Form.:
C21H26N2O7S
Mol. Mass.:
450.505
SMILES:
COc1ccc(cc1)S(=O)(=O)NC(CC(=O)N1CCC2(CC1)OCCO2)c1ccco1
Structure:
Search PDB for entries with ligand similarity: