Reaction Details Report a problem with these data
Target
Cathepsin S
Ligand
BDBM41362
Substrate
n/a
Meas. Tech.
Cathepsin S dose-response confirmation
IC50
>50000±0 nM
Citation
 PubChem, PC Cathepsin S dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Cathepsin S
Synonyms:
CATS_HUMAN | CTSS | Cathepsin S (Cat S) | cathepsin S preproprotein
Type:
Protein
Mol. Mass.:
37507.38
Organism:
Homo sapiens (Human)
Description:
P25774
Residue:
331
Sequence:
MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI
  
Inhibitor
Name:
BDBM41362
Synonyms:
3-(4-chlorophenyl)-N-(3-ethoxypropyl)-1-methyl-5-thieno[2,3-c]pyrazolecarboxamide | 3-(4-chlorophenyl)-N-(3-ethoxypropyl)-1-methyl-thieno[2,3-c]pyrazole-5-carboxamide | 3-(4-chlorophenyl)-N-(3-ethoxypropyl)-1-methylthieno[2,3-c]pyrazole-5-carboxamide | MLS000117302 | SMR000094252 | cid_5307886
Type:
Small organic molecule
Emp. Form.:
C18H20ClN3O2S
Mol. Mass.:
377.888
SMILES:
CCOCCCNC(=O)c1cc2c(nn(C)c2s1)-c1ccc(Cl)cc1
Structure:
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