Reaction Details Report a problem with these data
Target
Cathepsin G
Ligand
BDBM41393
Substrate
n/a
Meas. Tech.
Cathepsin G dose-response confirmation
IC50
5321.6±290.42 nM
Citation
 PubChem, PC Cathepsin G dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Cathepsin G
Synonyms:
CATG_HUMAN | CG | CTSG
Type:
PROTEIN
Mol. Mass.:
28860.08
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469016
Residue:
255
Sequence:
MQPLLLLLAFLLPTGAEAGEIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSNINVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIFGSYDPRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIRTTMRSFKLLDQMETPL
  
Inhibitor
Name:
BDBM41393
Synonyms:
MLS000087427 | N-(2-morpholin-4-ylethyl)-4,5-dihydrobenzo[g][1,2]benzoxazole-3-carboxamide | N-(2-morpholin-4-ylethyl)-4,5-dihydronaphtho[2,1-d]isoxazole-3-carboxamide | N-(2-morpholinoethyl)-4,5-dihydrobenz[g]indoxazene-3-carboxamide | N-[2-(4-morpholinyl)ethyl]-4,5-dihydrobenzo[g][1,2]benzoxazole-3-carboxamide | SMR000023650 | cid_3236780
Type:
Small organic molecule
Emp. Form.:
C18H21N3O3
Mol. Mass.:
327.3776
SMILES:
O=C(NCCN1CCOCC1)c1noc-2c1CCc1ccccc-21
Structure:
Search PDB for entries with ligand similarity: