Reaction Details Report a problem with these data
Target
Cathepsin G
Ligand
BDBM35509
Substrate
n/a
Meas. Tech.
Cathepsin G dose-response confirmation
IC50
2522.08±45.5758 nM
Citation
 PubChem, PC Cathepsin G dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Cathepsin G
Synonyms:
CATG_HUMAN | CG | CTSG
Type:
PROTEIN
Mol. Mass.:
28860.08
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469016
Residue:
255
Sequence:
MQPLLLLLAFLLPTGAEAGEIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSNINVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIFGSYDPRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIRTTMRSFKLLDQMETPL
  
Inhibitor
Name:
BDBM35509
Synonyms:
2-thiophenecarboxylic acid [5-amino-1-(4-methoxyphenyl)sulfonyl-3-pyrazolyl] ester | 5-amino-1-(4-methoxyphenylsulfonyl)-1H-pyrazol-3-yl thiophene-2-carboxylate | 5-amino-1-[(4-methoxyphenyl)sulfonyl]-1H-pyrazol-3-yl thiophene-2-carboxylate | CHEMBL243314 | MLS000086044 | SMR000021572 | [5-amino-1-(4-methoxyphenyl)sulfonylpyrazol-3-yl] thiophene-2-carboxylate | [5-azanyl-1-(4-methoxyphenyl)sulfonyl-pyrazol-3-yl] thiophene-2-carboxylate | cid_3240114 | thiophene-2-carboxylic acid [5-amino-1-(4-methoxyphenyl)sulfonyl-pyrazol-3-yl] ester
Type:
Small organic molecule
Emp. Form.:
C15H13N3O5S2
Mol. Mass.:
379.411
SMILES:
COc1ccc(cc1)S(=O)(=O)n1nc(OC(=O)c2cccs2)cc1N
Structure:
Search PDB for entries with ligand similarity: