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Target
Sphingosine 1-phosphate receptor 2
Ligand
BDBM1883
Substrate
n/a
Meas. Tech.
Dose Response Cell Based Assay for Agonists of the S1P2 Receptor
EC50
2413±n/a nM
Citation
 PubChem, PC Dose Response Cell Based Assay for Agonists of the S1P2 Receptor PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 2
Synonyms:
EDG5 | S1P2 | S1PR2 | S1PR2_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-5 | Sphingosine-1-phosphate receptor 2 | ndothelial differentiation G-protein coupled receptor 5
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38883.16
Organism:
Homo sapiens (Human)
Description:
Membranes isolated from S1P2-transfected CHO cells were used in ligand binding assay.
Residue:
353
Sequence:
MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV
  
Inhibitor
Name:
BDBM1883
Synonyms:
2-amino-1-(1,3-benzodioxol-5-ylmethyl)-N-butan-2-yl-3-pyrrolo[3,2-b]quinoxalinecarboxamide | 2-amino-1-(1,3-benzodioxol-5-ylmethyl)-N-butan-2-ylpyrrolo[3,2-b]quinoxaline-3-carboxamide | 2-amino-1-piperonyl-N-sec-butyl-pyrrolo[3,2-b]quinoxaline-3-carboxamide | 2-azanyl-1-(1,3-benzodioxol-5-ylmethyl)-N-butan-2-yl-pyrrolo[3,2-b]quinoxaline-3-carboxamide | MLS000040138 | SMR000042656 | cid_662039
Type:
n/a
Emp. Form.:
C23H23N5O3
Mol. Mass.:
417.4604
SMILES:
CCC(C)NC(=O)c1c(N)n(Cc2ccc3OCOc3c2)c2nc3ccccc3nc12
Structure:
Search PDB for entries with ligand similarity: