Reaction Details Report a problem with these data
Target
Alkaline phosphatase, germ cell type
Ligand
BDBM41877
Substrate
n/a
Meas. Tech.
Luminescent assay for identification of inhibitors of human intestinal alkaline phosphatase
IC50
>10000±n/a nM
Citation
 PubChem, PC Luminescent assay for identification of inhibitors of human intestinal alkaline phosphatase PubChem Bioassay (2009)[AID] 
Target
Name:
Alkaline phosphatase, germ cell type
Synonyms:
ALPG | ALPPL | ALPPL2 | Alkaline phosphatase placental-like | PPBN_HUMAN | placental-like alkaline phosphatase preproprotein
Type:
PROTEIN
Mol. Mass.:
57374.31
Organism:
Homo sapiens (Human)
Description:
ChEMBL_29964
Residue:
532
Sequence:
MQGPWVLLLLGLRLQLSLGIIPVEEENPDFWNRQAAEALGAAKKLQPAQTAAKNLIIFLGDGMGVSTVTAARILKGQKKDKLGPETFLAMDRFPYVALSKTYSVDKHVPDSGATATAYLCGVKGNFQTIGLSAAARFNQCNTTRGNEVISVMNRAKKAGKSVGVVTTTRVQHASPAGAYAHTVNRNWYSDADVPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPDDYSQGGTRLDGKNLVQEWLAKHQGARYVWNRTELLQASLDPSVTHLMGLFEPGDMKYEIHRDSTLDPSLMEMTEAALLLLSRNPRGFFLFVEGGRIDHGHHESRAYRALTETIMFDDAIERAGQLTSEEDTLSLVTADHSHVFSFGGYPLRGSSIFGLAPGKARDRKAYTVLLYGNGPGYVLKDGARPDVTESESGSPEYRQQSAVPLDGETHAGEDVAVFARGPQAHLVHGVQEQTFIAHVMAFAACLEPYTACDLAPRAGTTDAAHPGPSVVPALLPLLAGTLLLLGTATAP
  
Inhibitor
Name:
BDBM41877
Synonyms:
4,5,6,7-tetrachloro-2-(1H-1,2,4-triazol-5-yl)isoindole-1,3-dione | 4,5,6,7-tetrachloro-2-(1H-1,2,4-triazol-5-yl)isoindoline-1,3-quinone | 4,5,6,7-tetrakis(chloranyl)-2-(1H-1,2,4-triazol-5-yl)isoindole-1,3-dione | MLS-0146264.0001 | cid_2975202
Type:
Small organic molecule
Emp. Form.:
C10H2Cl4N4O2
Mol. Mass.:
351.96
SMILES:
Clc1c2C(=O)N(C(=O)c2c(Cl)c(Cl)c1Cl)c1nnc[nH]1
Structure:
Search PDB for entries with ligand similarity: