Reaction Details Report a problem with these data
Target
Bifunctional epoxide hydrolase 2
Ligand
BDBM41930
Substrate
n/a
Meas. Tech.
sEH_DR_Inh_Infinite200_Fluorescence_01072008
IC50
265.2±n/a nM
Citation
 PubChem, PC sEH_DR_Inh_Infinite200_Fluorescence_01072008 PubChem Bioassay (2008)[AID] 
Target
Name:
Bifunctional epoxide hydrolase 2
Synonyms:
Cytosolic epoxide hydrolase 2 | EBifunctional epoxide hydrolase 2 | EPHX2 | Epoxide hydratase | HYES_HUMAN | Lipid-phosphate phosphatase | Soluble epoxide hydrolase (sEH) | epoxide hydrolase 2, cytoplasmic
Type:
Enzyme
Mol. Mass.:
62613.07
Organism:
Homo sapiens (Human)
Description:
P34913
Residue:
555
Sequence:
MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDARNPPVVSKM
  
Inhibitor
Name:
BDBM41930
Synonyms:
MLS000324870 | N-[2-[2-[(2-chlorophenyl)methylidene]hydrazinyl]-2-oxidanylidene-ethyl]-N-(2-methylphenyl)benzamide | N-[2-[2-[(2-chlorophenyl)methylidene]hydrazinyl]-2-oxoethyl]-N-(2-methylphenyl)benzamide | N-[2-[N'-(2-chlorobenzylidene)hydrazino]-2-keto-ethyl]-N-(o-tolyl)benzamide | N-{2-[2-(2-chlorobenzylidene)hydrazino]-2-oxoethyl}-N-(2-methylphenyl)benzamide | SMR000163117 | cid_11948769
Type:
Small organic molecule
Emp. Form.:
C23H20ClN3O2
Mol. Mass.:
405.877
SMILES:
Cc1ccccc1N(CC(=O)NN=Cc1ccccc1Cl)C(=O)c1ccccc1 |w:12.12|
Structure:
Search PDB for entries with ligand similarity: